K A Yamaoka, S Tsukidate, M Higaki, N Miyasaka, K Fujita
{"title":"免疫双丝虫排泄和分泌抗原诱导Fc epsilon RII/CD23对人T细胞的作用。","authors":"K A Yamaoka, S Tsukidate, M Higaki, N Miyasaka, K Fujita","doi":"10.1159/000235460","DOIUrl":null,"url":null,"abstract":"<p><p>We investigated the capacity of excretory and secretory antigen (ES) derived from living filarial worms in the induction of CD23 expression on human peripheral blood T cells by using flow cytometry. ES (10 micrograms/ml) significantly induced the expression of CD23 on human T cells. Moreover, increased CD23 expression was completely abolished by preincubation with specific antibody to ES. The results suggest that ES might play a certain role in IgE antibody production by induction of CD23 expression on T cells.</p>","PeriodicalId":13810,"journal":{"name":"International archives of allergy and applied immunology","volume":"95 1","pages":"92-3"},"PeriodicalIF":0.0000,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000235460","citationCount":"4","resultStr":"{\"title\":\"Induction of Fc epsilon RII/CD23 on human T cells by excretory and secretory antigen of Dirofilaria immitis.\",\"authors\":\"K A Yamaoka, S Tsukidate, M Higaki, N Miyasaka, K Fujita\",\"doi\":\"10.1159/000235460\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We investigated the capacity of excretory and secretory antigen (ES) derived from living filarial worms in the induction of CD23 expression on human peripheral blood T cells by using flow cytometry. ES (10 micrograms/ml) significantly induced the expression of CD23 on human T cells. Moreover, increased CD23 expression was completely abolished by preincubation with specific antibody to ES. The results suggest that ES might play a certain role in IgE antibody production by induction of CD23 expression on T cells.</p>\",\"PeriodicalId\":13810,\"journal\":{\"name\":\"International archives of allergy and applied immunology\",\"volume\":\"95 1\",\"pages\":\"92-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1159/000235460\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International archives of allergy and applied immunology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000235460\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International archives of allergy and applied immunology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000235460","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Induction of Fc epsilon RII/CD23 on human T cells by excretory and secretory antigen of Dirofilaria immitis.
We investigated the capacity of excretory and secretory antigen (ES) derived from living filarial worms in the induction of CD23 expression on human peripheral blood T cells by using flow cytometry. ES (10 micrograms/ml) significantly induced the expression of CD23 on human T cells. Moreover, increased CD23 expression was completely abolished by preincubation with specific antibody to ES. The results suggest that ES might play a certain role in IgE antibody production by induction of CD23 expression on T cells.
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