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摘要

美国国立卫生研究院听神经瘤共识发展会议汇集了神经外科医生、放射外科医生、耳科医生、神经科医生、听力学家、耳鼻喉科医生和其他卫生保健专业人员以及公众,以达成以下协议:(1)定义听神经瘤的临床类型;(2)筛查和诊断的有用程序;(3)治疗疾病和治疗并发症的可用选择。(4)进一步研究的临床和生物学重点领域。经过两天的专家介绍和听众讨论,一个共识小组权衡了证据并准备了他们的共识声明。在他们的发现中,专家组得出结论:(1)前庭神经鞘瘤比听神经瘤更合适,因为这些肿瘤由雪旺细胞组成,通常涉及前庭神经而不是第8颅神经的听神经分裂;(2)前庭神经鞘瘤的治疗必须个体化,需要一个经验丰富、整合良好的多学科团队;(3)手术仍然是治疗的选择,但需要对所有治疗方案的相对收益和风险进行研究,包括药物和其他替代医学治疗,如肿瘤抑制药物;(4)前庭神经鞘瘤的手术治疗应包括术中常规面神经监测;(5)所有新诊断为前庭神经鞘瘤的患者应仔细考虑2型神经纤维瘤病(NF2),一旦发现,应向所有相关家庭成员提供遗传评估和咨询;(6)所有前庭神经鞘瘤患者的登记,无论是接受观察还是积极治疗,都应该建立。
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Acoustic neuroma.

The National Institutes of Health Consensus Development Conference on Acoustic Neuroma brought together neurosurgeons, radiosurgeons, otologists, neurologists, audiologists, otolaryngologists, and other health care professionals as well as the public to reach agreement (1) on defining the clinical types of acoustic neuroma, (2) on which procedures are useful for screening and diagnosis, (3) on the options available for managing the disorder as well as the complications of treatment, and (4) on the key clinical and biological areas for future research. Following 2 days of presentations by experts and discussion by the audience, a consensus panel weighed the evidence and prepared their consensus statement. Among their findings, the panel concluded that (1) the term vestibular schwannoma is preferred over acoustic neuroma as these tumors are composed of Schwann cells and typically involve the vestibular rather than the acoustic division of the 8th cranial nerve; (2) treatment for vestibular schwannoma must be individualized and requires an experienced, well-integrated, multidisciplinary team approach; (3) surgery remains the treatment of choice, but research is needed on the relative benefits and risks of all management options, including pharmaceutical and other alternative medical treatments such as tumor suppressing agents; (4) routine intraoperative monitoring of the facial nerve should be included in surgical therapy for vestibular schwannoma; (5) neurofibromatosis 2 (NF2) should be carefully considered in all patients newly diagnosed with vestibular schwannoma, and, when found, genetic evaluation and counseling should be provided for all relevant family members; and (6) a registry for all patients with vestibular schwannoma, whether undergoing observation or active management, should be established.

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Acoustic neuroma. Triglyceride, high density lipoprotein, and coronary heart disease. Triglyceride, high density lipoprotein, and coronary heart disease. Diagnosis and treatment of early melanoma. NIH Consensus Development Conference. January 27-29, 1992. Acoustic neuroma.
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