L Hadas, A Vosecková, F Duska, J Vizda, P Kafka, E Urbanová
{"title":"[六基斯,(t-丁基异硝基/锝,99mTc-TBI),一种冷灶心脏放射性药物及其在体内的分布]。","authors":"L Hadas, A Vosecková, F Duska, J Vizda, P Kafka, E Urbanová","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The distribution of coldfocal cardiopharmacological substance 99mTc-TBI has been studied on a total of 14 dogs in relation to the healthy heart tissue. The quality heart scan resulted from the use of 99mTc-TBI. It may be performed 30 min after the administration of mentioned substance, when its blood activity is smaller than 10% activity of myocardium From the other organs, the myocardium scan may be influenced negatively with only liver which achieves 200% activity of left heart ventricle what is evidently consequential in worse imaging of \"lower\" ischemic lesions. These results justify us to conclude that the 99mTc-TBI is a substance suitable for scintigraphical imaging of myocardium.</p>","PeriodicalId":76515,"journal":{"name":"Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum","volume":"34 5","pages":"561-70"},"PeriodicalIF":0.0000,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Hexakis, (t-butylisonitryl/technetium, 99mTc-TBI), a cold-focal cardiac radiopharmaceutic agent and its distribution in the body].\",\"authors\":\"L Hadas, A Vosecková, F Duska, J Vizda, P Kafka, E Urbanová\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The distribution of coldfocal cardiopharmacological substance 99mTc-TBI has been studied on a total of 14 dogs in relation to the healthy heart tissue. The quality heart scan resulted from the use of 99mTc-TBI. It may be performed 30 min after the administration of mentioned substance, when its blood activity is smaller than 10% activity of myocardium From the other organs, the myocardium scan may be influenced negatively with only liver which achieves 200% activity of left heart ventricle what is evidently consequential in worse imaging of \\\"lower\\\" ischemic lesions. These results justify us to conclude that the 99mTc-TBI is a substance suitable for scintigraphical imaging of myocardium.</p>\",\"PeriodicalId\":76515,\"journal\":{\"name\":\"Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum\",\"volume\":\"34 5\",\"pages\":\"561-70\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Hexakis, (t-butylisonitryl/technetium, 99mTc-TBI), a cold-focal cardiac radiopharmaceutic agent and its distribution in the body].
The distribution of coldfocal cardiopharmacological substance 99mTc-TBI has been studied on a total of 14 dogs in relation to the healthy heart tissue. The quality heart scan resulted from the use of 99mTc-TBI. It may be performed 30 min after the administration of mentioned substance, when its blood activity is smaller than 10% activity of myocardium From the other organs, the myocardium scan may be influenced negatively with only liver which achieves 200% activity of left heart ventricle what is evidently consequential in worse imaging of "lower" ischemic lesions. These results justify us to conclude that the 99mTc-TBI is a substance suitable for scintigraphical imaging of myocardium.