P P Liberski, H Kwieciński, M Barcikowska, B Mirecka, J Kulczycki, E Kida, P Brown, D C Gajdusek
{"title":"克雅氏病(CJD)病程短,伴有朊蛋白(PrP)斑块。","authors":"P P Liberski, H Kwieciński, M Barcikowska, B Mirecka, J Kulczycki, E Kida, P Brown, D C Gajdusek","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>We report here PrP-immunohistochemistry performed on brains from CJD cases from Poland. Only one out of five definitive CJD cases exhibited typical PrP-immunoreactive kuru-like plaques and this was case of a short duration. Thus, we confirmed the low percentage of PrP plaques in CJD of Eastern and Central European origin.</p>","PeriodicalId":76310,"journal":{"name":"Patologia polska","volume":"42 4","pages":"115-8"},"PeriodicalIF":0.0000,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Creutzfeldt-Jakob disease (CJD) of a short duration with prion protein (PrP) plaques.\",\"authors\":\"P P Liberski, H Kwieciński, M Barcikowska, B Mirecka, J Kulczycki, E Kida, P Brown, D C Gajdusek\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We report here PrP-immunohistochemistry performed on brains from CJD cases from Poland. Only one out of five definitive CJD cases exhibited typical PrP-immunoreactive kuru-like plaques and this was case of a short duration. Thus, we confirmed the low percentage of PrP plaques in CJD of Eastern and Central European origin.</p>\",\"PeriodicalId\":76310,\"journal\":{\"name\":\"Patologia polska\",\"volume\":\"42 4\",\"pages\":\"115-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Patologia polska\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Patologia polska","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Creutzfeldt-Jakob disease (CJD) of a short duration with prion protein (PrP) plaques.
We report here PrP-immunohistochemistry performed on brains from CJD cases from Poland. Only one out of five definitive CJD cases exhibited typical PrP-immunoreactive kuru-like plaques and this was case of a short duration. Thus, we confirmed the low percentage of PrP plaques in CJD of Eastern and Central European origin.