2014-2017年亚当马利克医院乳腺癌患者月经初潮特征分析

cynthia ervina, Dedy Hermansyah
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摘要

背景。乳腺癌是世界上诊断最多的癌症之一。当乳腺细胞异常生长并变成恶性肿瘤时,乳腺癌就开始了。在印度尼西亚,乳腺癌是女性中诊断最多的癌症。到目前为止,乳腺癌的病因还没有被确定。有很多因素会增加患乳腺癌的风险,其中之一就是月经初潮的年龄过早。目标。本研究旨在获取RSUP Haji Adam Malik 2014-2017年乳腺癌患者月经初潮年龄的特征。方法。本研究采用描述性观察法设计。采用全采样技术进行采样。结果。从总体特征来看,大多数乳腺癌患者年龄在40-49岁(38.5%),高中毕业(45.2%),无业(66.3%),无家族史(94.2%)。大多数患者为体育场IIIB乳腺癌(41.3%)。组织病理学诊断最多的是浸润性导管癌(78.8%)。大多数乳腺癌患者雌激素受体阴性(67.3%)、孕激素受体阴性(67.3%)、her2阴性(66.3%)、ki-67阳性(67.3%)。53例乳腺癌患者(51%)月经初潮早。从初潮的年龄来看,初潮早的患者多为三期乳腺癌,但初潮的年龄在组织病理学和免疫组织化学上并没有给出具体的特征。结论。初潮年龄在分期上具有特异性,但在组织病理学和免疫组织化学上没有特异性。
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Breast Cancer Patient Characeristics By Menarche In Adam Malik Hospital 2014-2017
Background. Breast cancer is one of the most diagnosed cancer in the world. Breast cancer starts when the breast cell grows abnormally and turns malignant. In Indonesia, breast cancer is the most diagnosed cancer in women. Up to now, the cause of breast cancer has not been identified yet. There are many factors that increase the risk of breast cancer, one of them is the early age of menarche. Objective. This study aims to obtain characteristics of breast cancer patients based on age of menarche in RSUP Haji Adam Malik in 2014-2017. Method. The study was designed in observational with descriptive method. The sampling had been done using total sampling technique. Results. Based on general characteristics, the majority of breast cancer patients are in the range of 40-49 years old (38,5%), graduated high school (45,2%), unemployed (66,3%), and do not have family history (94,2%). Majority of patients have stadium IIIB breast cancer (41,3%). The most diagnosed histopathology is Invasive Ductal Carcinoma (78,8%). Majority of breast cancer patients have negative estrogen receptor (67,3%), negative progesterone receptor (67,3%), negative her2 (66,3%) and positive ki-67 (67,3%). Fifty three breast cancer patients (51%) have early menarche. Based on the age of menarche, the patient with early menarche mostly has stage three breast cancer, but the age of menarche does not give a specific characteristic in histopathology and immunohistochemistry. Conclusion. Age of menarche gives specific characteristic in staging but not in histopathology and immunohistochemistry.
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