腹主动脉及其分支手术麻醉支持的优化

Adilet Kusainov
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摘要

背景:主动脉的病理包括主动脉瘤、缩窄、夹层、动脉粥样硬化性疾病和主动脉炎。腹主动脉修复仅有的两种循证治疗选择是血管内手术和开放手术。麻醉方法和药物可能影响手术修复腹主动脉及其分支的结果。目的:评价不同镇痛方案和局部、区域或全身麻醉在腹主动脉及其分支手术修复患者的“优化”手术效果中的应用。方法:在本综述中,检索Pubmed/MEDLINE、Google Scholar、Web of Science、Scopus、Cochrane Library等常用数据库中以“腹主动脉”、“手术”、“主动脉分支”为关键词并结合“涉及麻醉”的英文研究。此次审查的结束日期是2022年11月。科学新颖性:最近的科学研究集中在使用先进的监测技术,如脑血氧仪和微透析,以提高麻醉管理在主动脉手术中的安全性和有效性。这些技术提供了更准确和实时的脑灌注和代谢信息,使麻醉师能够更有效地识别和管理潜在的并发症,如脑缺血。此外,使用右美托咪定和瑞芬太尼等药物已被证明可以降低术后谵妄和认知功能障碍的风险,进一步改善患者的预后。结论:主动脉手术是一项复杂且高风险的手术,需要仔细的麻醉管理,以确保患者的安全和最佳结果。随着麻醉技术和监测技术的不断进步,我们有理由对主动脉手术的未来和改善患者预后的前景持乐观态度。麻醉师在这一过程中起着至关重要的作用,与手术团队密切合作,在整个手术过程中提供安全有效的麻醉,并确保患者在术后接受适当的疼痛管理和其他支持性护理
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Optimising anesthesia support during operations on the abdominal aorta and its branches
Background: Pathology of the aorta includes aortic aneurysms, coarctation, dissection, atherosclerotic disease, and aortitis. The only two evidence-based treatment options for abdominal aortic repair are endovascular and open surgery. The anesthetic approach and medications may impact the outcomes of the surgical repair of the abdominal aorta and its branches. Aim: to evaluate the use of various analgesic regimens and local, regional, or general anesthesia in "optimising" surgical outcomes in patients undergoing surgical repair of the abdominal aorta and its branches. Methods: In this review, English studies from common databases such as Pubmed/MEDLINE, Google Scholar, Web of Science, Scopus, and the Cochrane Library with the keywords "Abdominal aorta," "operations," "aortic branches," combined with keywords, involving " anesthesia were involved." The end date for this review was November 2022. Scientific novelty: Recent scientific studies have focused on the use of advanced monitoring technologies such as cerebral oximetry and microdialysis to improve the safety and efficacy of anesthesia management in aortic surgery. These technologies provide more accurate and real-time information about cerebral perfusion and metabolism, allowing the anesthesiologist to identify and manage potential complications such as cerebral ischemia more effectively. Additionally, the use of pharmacological agents such as dexmedetomidine and remifentanil has been shown to reduce the risk of postoperative delirium and cognitive dysfunction, further improving patient outcomes. Conclusion: Aortic surgery is a complex and high-risk procedure that requires careful management of anesthesia to ensure patient safety and optimal outcomes. With ongoing advances in anesthesia techniques and monitoring technologies, there is reason to be optimistic about the future of aortic surgery and the prospects for improved patient outcomes. The anesthesiologist plays a critical role in this process, working closely with the surgical team to provide safe and effective anesthesia throughout the procedure and ensuring that the patient receives appropriate pain management and other supportive care in the postoperative period
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