硝酸甘油经皮贴片:有利于抢救术后部分皮瓣坏死,方法简单有效

Manohar K. Malviya, Sameer Soni, Dipangi Gupta
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引用次数: 0

摘要

组织移植手术(筋膜皮瓣、蒂皮瓣、游离皮瓣或肌皮皮瓣局部移位)后的手术并发症大多与血管血栓形成有关,通常发生在手术后3天内。静脉充血通常导致水肿和皮肤颜色变深。早期静脉梗阻时,针刺会引起快速的深色血出血,动脉梗阻或痉挛会引起出血。患者和方法:这是一项前瞻性研究,于2018年1月至2021年2月在印度chirayu医学院博帕尔医院整形外科进行。本研究包括年龄在13岁至70岁的患者,他们在身体的任何部位接受皮瓣重建手术(筋膜皮蒂皮瓣,自由皮瓣,局部转位皮瓣或肌皮皮瓣)。将NTG贴片贴于受损皮瓣的皮肤表面,观察皮瓣功能不全。结果:本研究共纳入50例皮瓣重建患者。其中34例(17例)出现皮肤改变,66例(33例)出现针刺处充血。每隔一段时间在皮瓣表面施用NTGpatches。随访1周后,82%(41例)皮瓣的变化被逆转,皮瓣保持健康。18%(9个)皮瓣部分坏死或完全坏死。结论:硝酸甘油贴片可明显减少皮瓣部分坏死。皮瓣存活率显著提高,并可防止皮瓣再次探查。它们的应用是一种简单、安全、有效的方法来帮助挽救皮瓣。
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Nitroglycerin transcutaneous patch: boon to salvaging post-operative partial flap necrosis, simple and effective method
Introduction: The majority of surgical complications after tissue transfer surgery (Localtransposition of the fasciocutaneous flap, Pedicle flap, Free flap or musculocutaneous flap) arerelated to vascular thrombosis, which usually occurs within 3 days of surgery. Venous congestionusually results in oedema and darkening of the skin colour. During early venous obstruction, aneedle stick will cause rapid bleeding of dark blood and arterial obstruction or spasm will causedelayed bleeding. Patients and methods: This is prospective study was carried out during theperiod from January 2018 to February 2021 at the Plastic surgery unit-Chirayu Medical College AndHospital Bhopal, India. This study included patients aged 13 to 70 years undergoing reconstructivesurgery with flaps (Fasciocutaneous Pedicle flap, Free flap, local transposition flap ormusculocutaneous flap) for the wounds at any part of the body. The NTG patch was applied over thecutaneous surface of the compromised flap and then flap insufficiency was observed. Results: Inthis study total of 50 patients with flaps reconstruction were included. Among which 34 %( 17patients) had skin changes and 66 % (33 patients) had congested bleed on needle prick. NTGpatches were applied on the flap surface at regular intervals. After 1 week follows up, the changes in82% (41) flaps were reversed back and the flap remained healthy. 18% (nine) flaps had partial andor complete necrosis. Conclusion: There was a marked reduction in partial flap necrosis in patientswho received nitroglycerin patch. The flap survival was significantly improved and prevents the re-exploration of flaps. Their application is a simple, safe, and effective way to help salvage the flaps.
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