慢性肾病患者的甲真菌病

N. Shipilova, I. Sergeeva
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摘要

慢性肾脏疾病(CKD)发生在15%的成年人中。本研究的目的是评估CKD患者接受血液透析的甲癣的发生和临床特征。该研究包括25例(51±22岁)CKD合并指甲改变合并血液透析慢性肾衰竭患者和25例(53.6±26.4岁)非CKD患者。对于CKD,“黄指甲”是典型的- 17例(68%),没有CKD -纵向条纹- 16例(64%)。32%的CKD患者和64%的非CKD患者被诊断为甲癣。8例糖尿病合并慢性肾病患者中,7例合并甲真菌病,1例合并慢性肾病合并甲真菌病不合并糖尿病。对于CKD患者,OSI指数为12 [9;[14], [8];[12],无CKD: OSI - 16 [12;[17]、[10];15)。CKD患者的甲真菌病比非CKD患者少见,这表明在血液透析患者中,指甲感染真菌对其变化的发展意义较小。
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Onychomycosis in patients with chronic kidney disease
Chronic kidney disease (CKD) occurs in 15% of adults. The aim of the study was to evaluate the occurrence and clinical features of onychomycosis in patients with CKD receiving hemodialysis. A study comprised 25 patients (51±22 years) with CKD and nail changes with chronic renal failure under haemodialysis and 25 patients (53.6 ± 26.4 years) without CKD. For CKD, «yellow nails» are typical – in 17 (68%), without CKD – longitudinal stripes – in 16 (64%). Onychomycosis was diagnosed in 32% of patients with CKD and 64% without CKD. Out of 8 patients with diabetes mellitus and CKD, 7 had onychomycosis, 1 patient with CKD and onychomycosis did not have diabetes mellitus. For patients with CKD, the OSI index was 12 [9; 14], SCIO 10 [8; 12], without CKD: OSI – 16 [12; 17], SCIO – 12 [10; 15]. Onychomycosis in patients with CKD is less common than in patients without CKD, which indicates a lesser significance of nail infection with fungi in the development of their changes in patients under hemodialysis.
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