自身免疫性甲状腺炎合并甲状腺功能亢进合并多发性肌炎1例

Rivista di neurologia Pub Date : 1991-01-01
F Stevanato, F Martinello, R Pesce, I V Terribile, A Saia, C P Trevisan
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引用次数: 0

摘要

一个年轻女性,在自身免疫性甲状腺炎伴甲状腺功能亢进期间,遭受了进行性四肢近端无力。伴随性多肌炎的诊断是通过血浆CPK的显著增加、肌电图的肌病发现和肌肉活检的炎症改变的清晰图像来表明的。类固醇治疗使甲状腺和肌肉症状完全恢复。在接下来的几个月里,病人出现了甲状腺炎的第二次发作,随后又出现了多肌炎的另一次发作。本文讨论了自身免疫性甲状腺炎与多发性肌炎不寻常关联的可能发病机制。
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[A case of polymyositis in autoimmune thyroiditis with hyperthyroidism].

A young woman, during an autoimmune thyroiditis with hyperthyroidism, suffered from progressive proximal weakness at her four limbs. The diagnosis of a concomitant polymyositis was indicated by a marked increase of plasma CPK, myopathic findings at EMG and a clearcut picture of inflammatory alterations at muscle biopsy. Steroid therapy brought a full recovery of both thyroid and muscular symptoms. In the following months, the patient suffered from a second episode of thyroiditis and subsequently from another poussée of polymyositis. The possible pathogenesis underlying the unusual association of an autoimmune thyroiditis with a polymyositis is discussed.

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