睡眠对阿尔茨海默病和其他痴呆症的影响。

M V Vitiello, J S Poceta, P N Prinz
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引用次数: 55

摘要

据估计,高达10%的老年人有临床上显著的认知缺陷。痴呆症背后的神经病理导致认知功能障碍和正常睡眠/觉醒模式的紊乱。在这里,我们报告了随着阿尔茨海默病(可能是最常见的痴呆症)严重程度的增加而出现的睡眠/觉醒模式的变化。此外,研究检查睡眠/觉醒模式在许多其他痴呆障碍进行了审查。
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Sleep in Alzheimer's disease and other dementing disorders.

It is estimated that up to 10% of the elderly population have clinically significant cognitive deficits. The neuronal pathologies that underlie the dementing disorders cause both cognitive dysfunction and disturbances in normal sleep/wake patterns. Here we report the changes in sleep/wake patterns seen with increasing severity of Alzheimer's disease, probably the most common dementing disorder. In addition, studies examining sleep/wake patterns in a number of other dementing disorders are reviewed.

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