鞘内高压罗哌卡因与布比卡因用于剖宫产的比较

U. Srivastava, K. Joshi, Amrita Gupta, Yogita Dwivedi, H. Anand, A. Kannaujia, Sathiyanarayanam Pilendram
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引用次数: 7

摘要

背景:罗哌卡因是最近引进的一种局部麻醉剂,其心脏毒性较小,麻醉时间较短,可能在产科有价值。本研究的目的是评价0.5%高压氧罗哌卡因在剖宫产术中脊髓麻醉的效果,并与高压氧布比卡因进行比较。方法:在这项双盲前瞻性随机研究中,比较高压氧罗哌卡因与高压氧布比卡因在单次剖宫产脊髓麻醉患者中的阻滞特性。80名产妇被随机分为两组。R组(n=39)接受15 mg含8.3%葡萄糖的0.5%高压罗哌卡因,B组(n=41)接受11 mg 0.5%高压布比卡因(市售制剂)。结果:R组感觉阻滞的发生速度稍慢,但两组运动阻滞的发生速度相近。r组感觉和运动阻滞消退较快,两组低血压及其他不良反应发生率相似。R组手术麻醉质量与b组无明显差异。结论:8.3%葡萄糖中15mg罗哌卡因与11mg 0.5%高压布比卡因对剖宫产的麻醉效果相当。
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Comparison Of Intrathecal Hyperbaric Ropivacaine And Bupivacaine For Caesarean Delivery
Background: Ropivacaine a recently introduced local anaesthetic with lesser cardiotoxicity and shorter duration of anaesthesia may be of value in obstetrics. Aim of this study was to evaluate efficacy of spinal anaesthesia with 0.5% hyperbaric ropivacaine during caesarean section and to compare with that of hyperbaric bupivacaine. Methods: In this double blind prospective randomized study, block characteristics of hyperbaric ropivacaine were compared with that of hyperbaric bupivacaine in patients receiving single shot spinal anaesthesia for caesarean delivery. Eighty parturients were randomly allocated to two groups. Group R (n=39) received 15 mg of 0.5% hyperbaric ropivacaine in 8.3% dextrose and group B (n=41) received 11 mg of 0.5% hyperbaric bupivacaine (commercially available preparation).Result: Onset of sensory block was slightly slower in group R but the speed of onset of motor block was similar in both groups. Regression of sensory and motor block was faster in group R. The incidence of hypotension and other side effects was similar in the two groups. Quality of surgical anaesthesia in group R was indistinguishable from that of group B. Conclusion: It was concluded that 15 mg of ropivacaine in 8.3% dextrose provided satisfactory anaesthesia for caesarean delivery similar to that with 11 mg of 0.5% hyperbaric bupivacaine.
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