复发性腹痛:孟加拉儿童肠道淋巴瘤的罕见表现

Md Shafiul Alam, M. Mazumder, M. Begum, -. Md Benzamin, Nadia Haq, Shariful Hasan, A. R. Rahman, Md. Saidul Islam
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摘要

在儿童中,胃肠道的原发性恶性肿瘤是罕见的,占所有儿科肿瘤的不到5%非霍奇金淋巴瘤(NHL)仍然是儿童消化道最常见的恶性肿瘤此外,小肠(PLI)非常罕见。它们的解剖分布和组织学表现与成人病例的常见模式不同。此病罕见,临床表现多变,在有治愈可能的情况下,早期发现较迟。PLI的常见表现为肠梗阻和肠套叠。3,4胃肠道NHL通常发生于回盲区粘膜下淋巴组织,经粘膜扩展,广泛累及局部肠系膜淋巴结,形成腹部肿物。NHL最常累及回盲瓣(35.8%),其次是小肠(31.3%)、大肠(19.4%)和多发性胃肠道(13.4%)在这里,我们提出了一个病例报告,以显示的情况下,患者患NHL的诊断被推迟。该患儿患有复发性腹痛(RAP),经各种治疗均未能好转。最后,他被诊断为原发性小肠非霍奇金淋巴瘤(PLI)。虽然PLI是一种非常罕见的儿童恶性肿瘤。《北方国际医学院学报》2019年7月1日第11卷第438-439页
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Recurrent Abdominal Pain: A Rare Presentation of Childhood Intestinal Lymphoma in a Bangladeshi Child
In children, primary malignant tumors of the gastrointestinal (GI) tract are rare and accounts less than 5% of all pediatric neoplasms.1 Non-Hodgkin’s lymphoma (NHL) remains the most common malignancy of the GI tract in children.2 Moreover small intestine (PLI) is very uncommon. They are different in anatomic distribution and histologic appearance compared to common patterns in adult cases. The disease is rare and having variable clinical presentation that delayed early detection when the possibility of cure exists. The common presentations of PLI are bowel obstruction and intussusception.3,4 NHL of the gastrointestinal tract usually arises in the submucosal lymphoid tissue of the ileocecal region, extendtransmuraly, and involve local mesenteric lymph nodes extensively, forming a bulky abdominal mass. NHL most frequently involved the ileocecal valve (35.8%), followed by the small bowel (31.3%), large bowel (19.4%) and multiple gastrointestinal involvements (13.4%).5 Here we present a case report to show the scenario of a patient suffering from NHL where diagnosis was delayed. The child was suffering from recurrent abdominal pain (RAP) and various treatment was offered but he could not improve. Finally, he was diagnosed as a case of primary non-Hodgkin's lymphoma of the small intestine (PLI). Though PLI is a very uncommon malignancy in childhood. Northern International Medical College Journal Vol. 11 No. 1 July 2019, Page 438-439
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