好牧场综合征伴肾小球基底膜抗体阴性的复发:临床病例

Revista médica de Chile Pub Date : 2019-03-01 DOI:10.4067/s0034-98872019000300390

R. Tagle, Trinidad Arancibia, Alexandra Fischman, S. Vázquez, J. Chahuan, Gonzalo P. Méndez, Juan Pablo Huidobro E.

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引用次数: 2

摘要

Goodpasture综合征被描述为单一发作的疾病实体。诊断为血浆或肾组织中出现抗肾小球基底(anti-GBM)抗体。虽然复发的抗gbm疾病是罕见的，它已报道在高达3%的病例。我们报告了一位63岁男性患者，其抗gbm疾病复发时血浆中未检测到抗gbm抗体，尽管发病时抗体呈阳性。Rev Med Chile 2019;147: 390 - 394)

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Recurrencia de Síndrome de Goodpasture con negativización de anticuerpos anti-membrana basal glomerular: Caso clínico

Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative anti-GBM antibodies in plasma is even less frequent We report a 63 years old male in whom anti-GBM disease recurred without detectable anti-GBM antibodies in plasma, despite having positive antibodies at the onset. (Rev Med Chile 2019; 147: 390-394)

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