腹主动脉瘤开腹手术中的降压策略

Alvian Chandra Budiman, Handayu Ganitafuri, B. Putro
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摘要

背景:主动脉瘤患者的开腹手术一直是每个麻醉师面临的挑战。大出血、血流动力学不稳定和周围灌注不足的风险是需要适当围手术期管理的一些原因。本病例报告的目的是描述腹主动脉瘤开腹手术中的容许性低血压策略。病例说明:65岁男性,放射学发现腹主动脉动脉瘤位于第3 -4腰椎水平,计划行开腹手术切除动脉瘤并主动脉移植。术前评估得出ASA III的身体状况。病人计划接受全身麻醉。通过放置动脉导管和中心静脉导管进行有创血流动力学监测。在主动脉夹钳手术之前,开始了容许性降压策略,使用滴定剂量的硝酸甘油降低收缩压,目标MAP为bb60 mmHg。出血处理采用血管内液体复苏,直到CVP达到7-8 mmHg的目标。释放主动脉钳后,滴注去甲肾上腺素,目标MAP为65 ~ 75 mmHg。术后,患者住进ICU。患者于术后第7天出院。结论:本病例通过采用容许性低血压策略维持患者血流动力学稳定,成功地完成了开放性动脉瘤切除术的围手术期治疗。手术过程中患者血流动力学状态的成功稳定导致了良好和快速的术后结果和恢复。
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Permissive Hypotension Strategy in Open-surgery of Abdominal Aortic Aneurysm
Background: Open-surgery in patients with aortic aneurysms has always been a challenge for every anesthesiologist. The risk of massive bleeding, hemodynamic instability, and peripheral perfusion insufficiency are some of the reasons for the need of appropriate perioperative management. The purpose of this case report is to describe the permissive hypotension strategy in open-surgery of abdominal aortic aneurysm. Case Ilustration: A 65-year-old man with radiologic findings of an aneurysm in the abdominal aorta at 3rd-4th lumbar vertebrae level was planned for open-surgery aneurysmectomy and aortic graft. Pre-operative assessment concluded the physical status of ASA III. Patient was planned to receive general anesthesia. Invasive hemodynamic monitoring was performed by placing an arterial line and a central venous catheter. Just before the aortic clamp procedure, permissive hypotension strategy was started by lowering systolic blood pressure using titrated doses of nitroglycerin with target MAP of >60 mmHg. Bleeding management was carried out with intravascular fluid resuscitation until the CVP target of 7-8 mmHg was achieved. When the aortic clamp was released, titrated dose of norepinephrine was administered with target MAP of 65-75 mmHg. Post-operatively, the patient was admitted to the ICU. The patient was discharged on the seventh post-operative day. Conclusion: This case demonstrated the successful perioperative management of an open surgery aneurysmectomy by maintaining the hemodynamic stability of the patient using permissive hypotension strategy. The successful stabilization of patient’s hemodynamic state during surgery resulted in a good and fast post-operative outcome and recovery.
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