"欧洲卫生保健和医学研究的生物银行、生物分子资源和生物信息学"

E. Bongcam-Rudloff
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引用次数: 0

摘要

对于未来的欧洲生物库和遗传流行病学项目,必须制定标准操作程序(SOP),以便有效地处理来自不同数据集的质量控制和数据合并问题。除了详细介绍样本收集的数据库外,还必须确保尽早获得重要的新研究工具,并随时提供最先进的技术。在这次演讲中,我将介绍一些背景信息,然后我会更详细地介绍一个数据库,我们建议这个数据库可以用来补充数据库,这些数据库集中于收集来自特征良好的人群的人类和动物样本。MolMeth(分子方法数据库)是一个数据库系统,为生命科学的实验室协议和方法编目。它在生物银行和系统生物学的大规模应用中具有特别的价值,但也为一般分子过程的科学交流提供了价值。它的设计是为了满足协议规范中对结构日益增长的需求,同时为贡献者提供便利,并为最终用户提供易于访问的功能。与当前的“平面文件”协议数据库相比,结构化协议提供了几个优势,例如允许根据不同的目的调整协议表示。它还为关于协议的自动推理提供了基础。
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"Biobanks, biomolecular resources and bioinformatics for health care and medical research in Europe"
For future European biobanks and genetic epidemiology projects it is essential to produce standards operating procedures (SOP) for efficient handling of the quality-control and data merging issues from different data sets. Along with databases detailing sample collections it is also necessary to ensure early access to important new research tools, and that state-of-the-art techniques are readily available. I will during this talk present some background information and I will then speak more in detail about a database that we propose can be used to complements the databases focused on the collection of samples of human and animal origin from well-characterized populations. MolMeth (Molecular Methods database) is a database system that catalogs laboratory protocols and methods for the life sciences. It is of particular value for large-scale applications in biobanks and systems biology, but also provides value in scientific communication about molecular procedures in general. It is designed to meet a growing need for structure in protocol specifications while offering convenience for contributors and easy access for end users. Structured protocols offer several advantages over current "flat file" protocol databases, such as allowing protocol presentation be adapted for different purposes. It also provides a foundation for automated reasoning regarding protocols.
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