In vivo activity of different feeding levels of Greater Celandine (Chelidonium Majus) extract on the growth performance and digestibility in broilers

The present research work was conducted to investigate the effect of Chelidonium Majus Extract (CME) on growth performance and digestibility in broiler chickens In vivo. 100-day-old chicks were used in study. Distributed in to 4 groups i.e. (A, B, C and D) 25 chicks in each group with 5 replicates. Group A kept as control without supplementation of (CME), group B with 0.5ml/L, group C with 1ml/L and group D with 1.5ml of supplemented with CME. Our fi ndings regarding growth performance showed signifi cantly (P<0.05) highest live body and Feed Conversion Ratio (FCR) in the birds of group C followed by D and B as compared to A group, signifi cantly (P<0.05) highest feed intake and dressing% was detected in various treated groups. Moreover, water consumption showed signifi cantly (P<0.05) increase in birds in group B as compared to C, D and A groups. Whereas decrease in mortality percentage was recorded in groups B and C as compared to A and D groups, however difference was non-signifi cant (P>0.05) between all treated groups. morbidity percentage showed signifi cantly (P<0.05) increased in A group as compared to B, C and D groups. Relative organs weight, spleen weight remained unaffected between all treatment groups. highest relative weight of gizzards and heart was observed in all treated groups; Similarly, maximum relative weight of liver was observed in C and D groups followed by A and B groups. Furthermore, digestibility of various nutrients, dry matter, crude protein showed signifi cantly (P<0.05) increased between various treatment groups, However, crude fi ber showed non-signifi cantly (P>0.05) difference in all treatment group. Likewise, ash matter was recorded signifi cantly (P<0.05) increased in C and D groups as compared to B and A groups. Furthermore, economically proved that more profi table in group C followed by groups A, B and D. Based on above results, it was concluded that providing Chelidonium majus extracts at the dose of 1 ml/litter had the better impact on growth performance, enhance the digestibility of various nutrients and best for the health aspects of broiler without any adverse effects. Research Article In vivo activity of different feeding levels of Greater Celandine (Chelidonium Majus) extract on the growth performance and digestibility in broilers Muhammad Usman Arain1, Gulfam Ali Mughal1, Shamsuddin Bughio2, Muhammad Bilawal Arain2*, Farman Siyal1, Muhammad Ali Arain4, Saba Nawaz Arain2 and Sarfraz Ali Vessar3 1Department of Animal Nutrition, Sindh Agriculture University, Tandojam, Pakistan 2Department of Veterinary Pharmacology, Sindh Agriculture University, Tandojam, Pakistan 3Department of Livestock Management, Sindh Agriculture University Tandojam, Pakistan 4University of Veterinary and Animal Sciences Lahore, Pakistan Received: 10 August, 2021 Accepted: 14 September, 2021 Published: 15 September, 2021 *Corresponding author: Muhammad Bilawal Arain, Department of Veterinary Pharmacology, Sindh Agriculture University, Tandojam, Pakistan, E-mail: