顺势疗法药物与激素替代治疗在甲状腺功能减退患者中的疗效比较及其合并症和危险因素的评估

Abina Augustine, M. Kumar
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摘要

简介:甲状腺激素合成和释放不足引起甲状腺功能减退。目前,甲状腺疾病是印度仅次于糖尿病的第二大常见内分泌疾病。女性的发病率高于男性。成年女性患病率为10%,成年男性患病率为3%。症状包括疲劳、嗜睡、疼痛、对寒冷的敏感性增加、便秘、过度嗜睡和心绞痛。甲状腺功能减退症患者如果遵循对抗性药物系统,则必须终生服用甲状腺激素替代药物,这些药物产生的副作用比甲状腺功能减退症更有害。如果顺势疗法的类似物能够刺激身体产生平衡水平的激素,那么甲状腺功能减退症患者就不需要终生更换激素了。方法:采用问卷调查法对60例甲状腺功能减退患者进行比较横断面研究,选取年龄在35 ~ 55岁之间已确诊为甲状腺功能减退的女性患者。他们被分为30名顺势疗法使用者和30名非顺势疗法使用者。采用实地调查方法,通过NSS营地调查获得对抗疗法使用者,顺势疗法使用者通过在SKHMC门诊就诊的患者获得顺势疗法使用者,问卷由患者填写。详细记录TFT值,身高,体重。记录每位患者的合并症并进行分析。对服药前后的症状变化及危险因素进行问卷调查。采用卡方检验对治疗组进行比较分析。结果:根据所进行的研究,观察到该病常见于35至39岁的患者。大多数患者有BMI升高(>25)等情况。在两组患者用药前后的症状缓解方面,顺势疗法服用者的症状缓解优于非服用者。在p值<0.01的统计分析中,许多症状在使用常规治疗后仍然存在。
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Effectiveness of Homoeopathic Medications in Comparison with Hormone Replacement Therapy in Hypothyroid Patients and Assessing their Comorbidity and Risk Factors
Introduction: Insufficient synthesis and release of thyroid hormone give rise to hypothyroidism. At present, thyroid disease forms the second most common endocrine disorder in India next to Diabetes mellitus. The women are affected more than men .10% prevalence in adult women and 3% in adult men. Symptoms include fatigue, lethargy, aches and pains, increased sensitivity to cold, constipation, excessive tendency to sleep and angina pain .Thyroid hormone replacement must be taken for the rest of their life in case of hypothyroidism patients, if they are following allopathic system of medicine and the side effects which these medicines produced are much harmful than hypothyroidism. If homoeopathic similimum could stimulate the body to produce its hormones in a balanced level, then the need for lifelong hormonal replacement in hypothyroidism becomes unnecessary. Methodology: A comparative cross sectional study has been conducted using questionnaire on 60 hypothyroid patients, in such a way that female patients who has been diagnosed with hypothyroidism between the ages of 35 to 55 were selected. They were divided as 30 homoeopathic users and 30 non-homoeopathic users. Field study was conducted and allopathic users were obtained through NSS camp surveys and homoeopathic users through patients attending SKHMC OPDs .The questionnaires were filled by the patient. Details regarding TFT values height, weight, were recorded. The comorbidities suffered by each patient were recorded and analysis was made. Regarding symptomatic change before and after medication and also risk factors were added in the questionnaire. Analysis was done using chi square test to compare the treatment groups. Result: From the study conducted, it has been observed that the disease is prevalent in patients between 35 and 39 years. Majority of the patients had conditions like increased BMI(>25). Regarding symptomatic relief in patients before and after medication in both groups, homoeopathic users got better symptomatic relief when compared with non-users. Many of the symptoms has persist even after using conventional treatment when statistically analysed with a p value <0.01.
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