Discrete-Time Blind Deconvolution for Distributed Parameter Systems with Dirichlet Boundary Input and Unbounded Output with Application to a Transdermal Alcohol Biosensor

A scheme for the blind deconvolution of blood or breath alcohol concentration from biosensor measured transdermal alcohol concentration based on a parabolic PDE with Dirichlet boundary input and point-wise boundary output is developed. The estimation of the convolution filter corresponding to a particular patient and device is formulated as a nonlinear least squares fit to data. The deconvolution is then formulated as a regularized linear-quadratic programming problem. Numerical results involving patient data are pre-