依托泊苷/阿霉素/顺铂(EAP)联合治疗不能手术的胃癌的有效性——一个经组织学证实的病例报告。

H Tahara, M Ogawa, Y Kido, H Shiozaki, I Ohashi, T Mori, M Sakurai
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引用次数: 0

摘要

我们在此报告一名55岁男性不可切除胃癌患者的组织学观察,他对依托泊苷/阿霉素/顺铂(EAP)化疗几乎完全应答。患者接受2个周期EAP治疗后再次手术,成功切除胃及邻近淋巴结。组织学结果显示,包括直接侵袭部位在内的主要肿瘤细胞已完全消失,取而代之的是再生的粘膜。转移性淋巴结肿瘤也被部分杀死,正如一群活的癌细胞被坏死组织条分开所表明的那样。这些发现使我们得出结论,EAP治疗对患者非常有效。
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The effectiveness of a combination of etoposide/adriamycin/cisplatin (EAP) against inoperable gastric cancer--report of a histologically proven case.

We report herein, the histological observations taken at initial laparotomy from a 55 year old man with unresectable gastric cancer who responded almost completely to chemotherapy with Etoposide/Adriamycin/Cisplatin (EAP). The patient underwent a second operation after 2 cycles of EAP therapy and the stomach and adjacent lymph nodes were successfully resected. Histologic findings showed that cancer cells in the main tumor including the site of direct invasion had completely disappeared and been replaced by regenerated mucosa. The metastatic lymph node tumor was also partially killed, as indicated by a cluster of viable cancer cells which was divided by a strip of necrotic tissue. These findings led us to conclude that EAP therapy was remarkably effective for the patient.

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The 73rd Annual Meeting of the Japan Surgical Society The 74th Annual Meeting of the Japan Surgical Society The beginnings of a “human science” The general rules for the gastric cancer study in surgery and pathology The 75th Annual Meeting of the Japan Surgical Society
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