仙台病毒P基因从重叠的开放阅读框中产生多种蛋白质。

Enzyme Pub Date : 1990-01-01 DOI:10.1159/000468762

J Curran, D Kolakofsky

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引用次数: 35

摘要

仙台病毒P基因包含重叠的开放阅读框(orf)，并且使用几种不寻常的机制从该基因的所有三个orf中产生多种蛋白质。这些包括使用非aug起始密码子，漏性核糖体扫描，似乎与扫描无关的核糖体起始和/或核糖体跳跃，以及mRNA编辑的一种形式。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Sendai virus P gene produces multiple proteins from overlapping open reading frames.

The Sendai virus P gene contains overlapping open reading frames (ORFs), and several unusual mechanisms are used to produce multiple proteins from all three ORFs of this gene. These include the use of a non-AUG start codon, leaky ribosomal scanning, what appears to be scanning-independent ribosomal initiation and/or ribosomal jumping, and a form of mRNA editing.

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