坚持治疗

Rob Horne
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摘要

©剑桥大学出版社2007。从服药到参加咨询会议,不遵医嘱被认为是医疗保健各个方面的一个重大问题。在过去的几十年里,关于这一主题的研究论文已经发表了数千篇,但不依从仍然是现代医疗保健中的一个关键挑战。研究和评论的主要焦点是长期医疗条件下的药物依从性。这不足为奇。在富裕国家,大多数卫生保健资源用于冠心病、糖尿病和哮喘等慢性病的管理。在这里,良好的结果既取决于良好的医疗护理,也取决于患者的自我管理。对于大多数这些情况,自我管理取决于药物的适当使用。然而,许多患者未能做到这一点。对药物不依从性发生率的估计范围在2-98%之间,部分原因是不同研究对依从性的定义和测量方式存在差异。大多数综述估计,30-50%的慢性疾病药物处方没有按照指示服用(Meichenbaum & Turk, 1987;Myers & Midence, 1998;世界卫生组织,2003年)。如果处方是合适的,那么这种程度的不依从性对提供、接受或资助医疗保健的人来说是一个问题,因为它不仅会浪费资源,还会错过获得治疗益处的机会(DiMatteo等人,2002)。不幸的是,有效的干预仍然难以捉摸(Haynes et al., 2002)。
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Adherence to Treatment
© Cambridge University Press 2007. Introduction Non-adherence is perceived to be a significant problem in all aspects of healthcare from taking medication to attending counselling sessions. Thousands of research papers have been published on the topic in the last few decades yet non-adherence remains a key challenge in modern healthcare. The main focus of research and reviews has been on adherence to medication prescribed for long-term medical conditions. This is hardly surprising. In affluent countries, most healthcare resources are devoted to the management of chronic diseases such as coronary heart disease, diabetes and asthma. Here, good outcomes depend as much on self-management by the patient as on good medical care and, for most of these conditions, self-management hinges on the appropriate use of medicines. However many patients fail to achieve this. Estimates of the incidence of non-adherence to medication range widely from 2–98%, partly because of differences in the way adherence is defined and measured across studies. Most reviews estimates that 30–50% of medication prescribed for chronic illness is not taken as directed (Meichenbaum & Turk, 1987; Myers & Midence, 1998; World Health Organization, 2003). If the prescription was appropriate, then this level of non-adherence is a concern for those providing, receiving or funding healthcare because it not only entails a waste of resources but also a missed opportunity for therapeutic benefit (DiMatteo et al., 2002). Unfortunately, effective interventions remain elusive (Haynes et al., 2002).
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