冠状醚络合热力学及膜活性

U. Mirkhodjaev, O. Yarishkin, U. Sharafutdinova, U. Toyirov, N. Atamuratova, A. K. Tashmukhamedova, Bekdjan Tashmukhamedov
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引用次数: 0

摘要

在络合数据的分析中使用热力学特性,可以给得到的数据一个明确的物理和化学解释。我们的研究使我们能够评估与所研究分子结构相似的化合物的复杂形成能力,并将有助于分析“结构-功能”。他们可以补充数据库的物理和化学性质的冠醚,并使预测只有“构建的化合物”。我们已经开发了一套可靠的程序,用于络合物形成,膜活性和热力学性质的电导分析的磺化衍生物- db18c6,二酰基衍生物- db18c6,4 ',4 '(5 ')-二甲氨基乙醇db18c6和双-邻甲氧基苯氧二乙醚。
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Thermodynamics of complexation and membrane activity of crown ethers
The use of thermodynamic characteristics in the analysis of data on complexation makes it possible to give the obtained data a definite physical and chemical interpretation. Our studies allow us to evaluate the complex forming abilities of compounds similar in structure to the molecules studied, and will help to analyze the "structure-function". They can replenish the database on the physical and chemical properties of crown ethers, and enable the prediction of only "constructed compounds". We have developed a reliable set of procedures for conductometric analysis of complex forming, membrane active and thermodynamic properties of sulfo derivatives-DB18C6, diacyl derivatives-DB18C6, 4’,4"(5")-dimethylaminoethanolDB18C6 and bis-o-methoxyphenoxy-diethyl ethers.
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