Z. Krátká, J. Paška, Veronika Šíblová, K. Licková, R. Lohynská, A. Čoček
{"title":"PET/ CT在头颈部肿瘤远处转移及继发性恶性肿瘤诊断中的应用","authors":"Z. Krátká, J. Paška, Veronika Šíblová, K. Licková, R. Lohynská, A. Čoček","doi":"10.48095/CCORL20216","DOIUrl":null,"url":null,"abstract":"Aim: Our goal was to assess our experience with accuracy of PET/ CT in the diagnostics of distant metastases and duplicity tumors in head and neck oncology. Methods: In total, 159 patients with a previously histologically verified malignant tumor of the head and neck underwent whole-body PET/ CT in our facility from 2016 to 2019. In 51 cases, we found out higher uptake of marked radiopharmaceutical (fluorodeoxyglucose) out of the head and neck region. In a retrospective study, we were evaluating the sensitivity and specificity of the method in the diagnostics of distant metastases and duplicities. Results: In our study, PET/ CT has sensitivity of 95.7% and specificity of 79.9% with positive and negative predictive values of 44.9% and 99.1% respectively. Conclusion: The method has a high sensitivity but lower specificity rate in the diagnostics of distant metastases (duplicity tumors) in head and neck oncology. Considering high radiation load and the price and availability of PET/ CT, it is necessary to consider the indication of this technique properly.","PeriodicalId":423943,"journal":{"name":"Otorinolaryngologie a foniatrie","volume":"115 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Use of PET/ CT in diagnostics of distant metastasis and secondary malignancies in head and neck oncology\",\"authors\":\"Z. Krátká, J. Paška, Veronika Šíblová, K. Licková, R. Lohynská, A. Čoček\",\"doi\":\"10.48095/CCORL20216\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Aim: Our goal was to assess our experience with accuracy of PET/ CT in the diagnostics of distant metastases and duplicity tumors in head and neck oncology. Methods: In total, 159 patients with a previously histologically verified malignant tumor of the head and neck underwent whole-body PET/ CT in our facility from 2016 to 2019. In 51 cases, we found out higher uptake of marked radiopharmaceutical (fluorodeoxyglucose) out of the head and neck region. In a retrospective study, we were evaluating the sensitivity and specificity of the method in the diagnostics of distant metastases and duplicities. Results: In our study, PET/ CT has sensitivity of 95.7% and specificity of 79.9% with positive and negative predictive values of 44.9% and 99.1% respectively. Conclusion: The method has a high sensitivity but lower specificity rate in the diagnostics of distant metastases (duplicity tumors) in head and neck oncology. Considering high radiation load and the price and availability of PET/ CT, it is necessary to consider the indication of this technique properly.\",\"PeriodicalId\":423943,\"journal\":{\"name\":\"Otorinolaryngologie a foniatrie\",\"volume\":\"115 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-03-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Otorinolaryngologie a foniatrie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.48095/CCORL20216\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Otorinolaryngologie a foniatrie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.48095/CCORL20216","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Use of PET/ CT in diagnostics of distant metastasis and secondary malignancies in head and neck oncology
Aim: Our goal was to assess our experience with accuracy of PET/ CT in the diagnostics of distant metastases and duplicity tumors in head and neck oncology. Methods: In total, 159 patients with a previously histologically verified malignant tumor of the head and neck underwent whole-body PET/ CT in our facility from 2016 to 2019. In 51 cases, we found out higher uptake of marked radiopharmaceutical (fluorodeoxyglucose) out of the head and neck region. In a retrospective study, we were evaluating the sensitivity and specificity of the method in the diagnostics of distant metastases and duplicities. Results: In our study, PET/ CT has sensitivity of 95.7% and specificity of 79.9% with positive and negative predictive values of 44.9% and 99.1% respectively. Conclusion: The method has a high sensitivity but lower specificity rate in the diagnostics of distant metastases (duplicity tumors) in head and neck oncology. Considering high radiation load and the price and availability of PET/ CT, it is necessary to consider the indication of this technique properly.