腹膜透析患者的生活质量及其影响因素

N. Nili, S. Seirafian, S. Hosseini, A. Atapour, Maryam Kazemi Naeini, M. Mortazavi
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摘要

近年来,人们对与健康相关的生活质量(HRQoL)作为终末期肾病(ESRD)患者临床疗效和治疗结果的主要指标的兴趣显著增加。本研究旨在确定影响腹膜透析(PD) ESRD患者生活质量(QoL)的因素。2019年5月至8月,对伊朗伊斯法罕Al-Zahra和Noor医院PD中心的PD患者进行了一项横断面研究。共有173例接受腹膜透析3个月以上的患者填写了经验证的36项简短健康调查问卷(SF-36)。从患者的医疗记录中收集基线人口统计细节和透析相关因素。患者总体生活质量评分为50.28±20.87。男性患者的生活质量评分高于女性患者(男性为58.18,女性为48.18;P = 0.04)。观察到透析频率与生活质量之间存在显著关联,每天透析三次可获得最高的生活质量(生活质量评分= 59.62;P = 0.047)。生活质量评分与残余肾功能呈显著正相关(P = 0.013)。个体经营患者的生活质量评分(60.95)高于家庭主妇(46.49)(P = 0.001)。生活质量评估应作为患者随访的一个组成部分,以评估治疗结果并实施可能的干预措施,以改善患者的生活质量。
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Quality of Life of Patients on Peritoneal Dialysis and Contributing Factors
In recent years, interest in Health-Related Quality of Life (HRQoL) as a major indicator of clinical efficacy and treatment outcome in patients of End-Stage Renal Disease (ESRD) has grown significantly. This study aimed to determine the contributing factors affecting the quality of life (QoL) of ESRD patients undergoing peritoneal dialysis (PD). A cross-sectional study was conducted on PD patients presented at PD centres of Al-Zahra and Noor hospitals in Isfahan, Iran, from May to August 2019. A total of 173 patients having peritoneal dialysis for more than 3 months filled the validated 36-item short-form health survey questionnaire (SF-36). Baseline demographic details and dialysis-related factors were collected from patients’ medical records. The overall QoL score of patients was 50.28 ± 20.87. Male patients had a higher QoL score than female patients (58.18 in males, compared to 48.18 in females; P = 0.04). A significant association between frequency of dialysis and quality of life was observed, where three sessions of dialysis per day yielded the highest quality of life (QoL score = 59.62; P = 0.047). A significant positive correlation was discovered between QoL score and residual renal function (P = 0.013). In addition, a higher QoL score was observed in self-employed patients (60.95), compared to housewives (46.49) (P = 0.001). QoL assessment should be included as an integral part of patient follow-up to evaluate treatment outcomes and implement possible interventions to improve patient’s quality of life.
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