配方和稳定性测试剂凝胶手SANITIZER提取黄瓜果实(Cucumis sativus L)。

Yani Ambari, Hanik Endah Paramita, Arista Wahyu Ningsih
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引用次数: 1

摘要

洗手液通常含有酒精和三氯生等化学物质。然而,如果持续使用这两种成分会造成危险,因此,handsanitizer抗菌产品采用了黄瓜果实的乙醇提取物,其中含有抗菌化合物,以减少这两种成分的使用。以黄瓜果乙醇提取物为原料制备洗手液凝胶配方,并测定其在贮存过程中的物理稳定性。黄瓜果乙醇提取物洗手液凝胶采用不同提取物浓度F1(1.5%)、F2(2.5%)、F3(3.5%)三种配方制备。感官测试的结果包括了这三种配方,即这三种配方在储存过程中没有变化。同质性检验的结果包括F1和F2,它们被认为是均匀的,而F3不均匀。pH值测试结果显示,在储存过程中,这三种物质的pH值一直下降到第3周,并在第4周再次升高。三种制剂的涂布性试验结果均满足凝胶制剂的要求,但在粘附性试验中,三种制剂均不满足凝胶制剂的粘附性要求。
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FORMULASI DAN UJI STABILITAS SEDIAAN GEL HAND SANITIZER EKSTRAK ETANOL BUAH MENTIMUN (Cucumis sativus L.)
Hand Sanitizers generally contain chemicals in the form of alcohol and triclosan. However, the use of these two ingredients can cause danger if they are used continuously, therefore the Hand Sanitizer antiseptic product was innovated using ethanol extract of cucumber fruit which contains antibacterial compounds to reduce the use of both ingredients. The purpose of this study was to make a Hand Sanitizer gel formulation from ethanol extract of cucumber fruit and to determine the physical stability of the preparation during storage. Hand Sanitizer Gel of cucumber fruit ethanol extract is made in three formulations withdifferent extract concentrations, namely F1 (1.5%), F2 (2.5%), and F3 (3.5%). The results of the organoleptic test included the three formulations, namely that the three of them did not change during storage. The results of the homogeneity test included F1 and F2 which were stated to be homogeneous while F3 was not homogeneous. The results of the pH test included that during storage the three had decreased until week 3 and increased thepH again at week 4. The results of the spreadabilitytest of the three preparations met the requirements for the gel preparation, but in the adhesion test the three preparations did not meet the adhesion requirements of the gel preparation.
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