压力和流量:它们是真正的血管神经效应器吗?

Blood vessels Pub Date : 1991-01-01 DOI:10.1159/000158857
J A Bevan
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引用次数: 5

摘要

向脉管系统供应的传出神经的活动导致血管平滑肌细胞张力的局部增加或减少,并伴有相应的直径变化。这会导致压力和流量的变化,这两者都影响血管壁,因此可能会将影响扩展到整个床层。由于血管床对压力敏感——压力的增加导致血管收缩——对血流敏感——压力的增加导致不同程度的收缩和松弛——最终结果必须反映它们之间的相互作用。因此,神经活动引起的动脉张力的直接变化通过伴随的血流和血压的变化而被修正并扩散到整个区域动脉系统。
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Pressure and flow: are these the true vascular neuroeffectors?

Activity of the efferent nerve supply to the vasculature results in local increases or decreases in the tone of the vascular smooth muscle cells with corresponding changes in diameter. This results in changes in pressure and flow, both of which, because they too influence the vascular wall, extend the influence potentially to the entire bed. As the vascular bed is sensitive to pressure - an increase causing vasoconstriction - and to flow - an increase causing variable amounts of contraction and relaxation - the final results must reflect their interaction. Thus, the direct changes in artery tone brought about by neural activity are modified and diffused throughout the entire regional arterial system by the concomitant changes in the flow and pressure of the blood.

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