超声图像深度学习诊断脂肪肝

Chunpeng Wu, Che-Lun Hung, Teng‐Yu Lee, Chun-Ying Wu, William C. Chu
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引用次数: 4

摘要

肝癌主要由乙型和丙型肝炎病毒感染引起。近年来,乙型和丙型肝炎的患病率已大大降低。由于不良的生活方式和饮食习惯,脂肪肝的患病率有所增加。脂肪肝可能逐渐取代病毒性肝炎成为肝癌的主要病因。超声图像通常是脂肪肝临床检查的主要检查点。本研究采用深度学习图像分割模型和图像纹理特征分析。首先从超声图像中提取纹理特征,然后对纹理特征进行模型训练,实现临床客观诊断。本研究使用的美国图像是从公共医疗中心美国机器收集的。收集235例患者的超声图像和肝纤维化扫描仪FibroScan。根据脂肪肝的分类和诊断的严重程度,本研究分为两部分。首先,将患者超声图像数据应用于图像切割模型训练和纹理特征提取。其次,将纹理特征值与脂肪肝严重程度分类模型训练与验证所对应的肝组织病理CAP结果进行比较。实验结果表明,该模型可以在特定仪器上预测脂肪肝疾病,曲线下面积达到0.8以上。
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Fatty Liver Diagnosis Using Deep Learning in Ultrasound Image
Liver cancer is mainly caused by hepatitis B and C virus infection. In recent years, the prevalence of hepatitis B and C has been greatly reduced. With poor lifestyle and eating habits, the prevalence of fatty liver disease has increased. Fatty liver disease perhaps gradually replaces viral hepatitis as the leading cause of liver cancer. Ultrasound images are usually the primary checkpoint for the clinical examination of the fatty liver. This study applied a deep learning image segmentation model and image texture feature analysis. First, texture features were extracted from ultrasound images, and then model training was performed on texture features to achieve the clinical objective diagnosis. The US images used in this study were collected from the public medical center US machine. Ultrasound images and FibroScan of liver fibrosis scanner were collected from 235 patients. According to the classification and diagnosis of the severity of fatty liver, this study is divided into two parts. First, the ultrasound image data of patients is applied to image cutting model training and texture feature extraction. Second, the value of the texture feature is compared with the results of liver tissue pathology CAP corresponding to the training and verification of the fatty liver severity classification model. The experimental results show that the proposed model can predict fatty liver disease on a specific instrument and can achieve an area under the curve above 0.8.
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