PET-CT在结性淋巴瘤诊断及评价中的作用

Ahmed Shaaban Hussain Muhammad, Mahmoud Kadry Elguindy, Muhammad Abol wafa Ahmed Amin
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引用次数: 0

摘要

背景:最常见的血液系统恶性肿瘤是恶性淋巴瘤,约占成人恶性肿瘤的8%。非霍奇金淋巴瘤和霍奇金病是两种类型的淋巴样肿瘤。目的:探讨正电子发射断层扫描/计算机断层扫描(PET/CT)在淋巴结性淋巴瘤诊断中的应用价值,分析18-FDG-PET/CT在淋巴结性淋巴瘤第一阶段的诊断效果,分析PET-CT在治疗过程中和治疗后监测患者中的作用,并探讨PET-CT在预测和发现复发中的作用。患者和方法:共30例患者,其中女性12例,男性18例;11例霍奇金病和19例非霍奇金病)组织学上证实的恶性淋巴瘤纳入本研究。根据PET/CT检查结果将患者分为三组。结果:CT诊断与PET/CT结果比较。目前的研究表明PET/CT在淋巴瘤分期、监测治疗反应和随访中的重要相关性。本研究证明了18F-FDG的重要性。当涉及到淋巴瘤的早期分期时,PET/CT已被证明是治疗淋巴瘤的一种有价值的工具。PET/CT在早期和延迟治疗反应评估中显示出实质性的影响。结论:本研究结果突出了18F-FDG PET/CT作为淋巴瘤第一分期技术的价值。比较PET/CT与诊断性CT对早期和延迟评估治疗反应具有重要意义。
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PET-CT Diagnostic and Evaluation Role in Patients with Nodal Lymphoma
Background : The most prevalent hematological malignancy is malignant lymphoma, which makes up ~8% of all adult malignancies. Non-Hodgkin lymphoma and Hodgkin disorder are two types of lymphoid neoplasms. Aim : To examine how positron emission tomography/computed tomography (PET/CT) may be used to diagnose nodal lymphoma, analyze the effectiveness of 18-FDG-PET/CT in the fi rst staging of nodal lymphoma, analyze the function of PET-CT in patient monitoring both during and after the therapeutic course, and examine the function of PET-CT in foretelling and spotting relapses. Patients and methods : A total of 30 patients (12 females and 18 males; 11 Hodgkin disorder and 19 non-Hodgkin disorder) with histologically con fi rmed malignant lymphoma were enrolled in this investigation. They were split into three groups judging by the outcomes of the PET/CT examination. Results : CT for diagnosis was compared with PET/CT results. The current study demonstrated the critical relevance of PET/CT in lymphoma staging, monitoring therapeutic response, and follow-up. The present investigation demonstrated the signi fi cance of 18F-FDG. When it comes to the early staging of lymphomas, PET/CT has shown to be a valuable tool in the treatment of lymphomas. PET/CT exhibited substantial effects on early and delayed therapy response evaluation. Conclusion : The outcomes of the present research highlighted the value of 18F-FDG PET/CT as a technique for the fi rst staging of lymphomas. Comparing PET/CT with diagnostic CT has major consequences for early and delayed evaluation of therapy response.
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