扫描激光声显微镜100 MHz衰减系数测量技术

K. Tervola, S. Foster, W. O’Brien
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引用次数: 22

摘要

摘要:目前还没有一种精确的方法来测量生物组织在100兆赫下的衰减系数。解决这一问题的方法有两种。一个涉及校准的查找表,另一个利用插入损耗的测量。对于后者,已经开发了一个程序,并使用已知的生物溶液进行了验证。插入损耗过程产生的衰减系数不确定度在5%以内,动态范围为4至28 dB/mm。插入损耗灵敏度为0.2 dB。N重要的组织表征特性是超声衰减系数,即声波通过材料传播时能量的减少。衰减包括吸收和散射。吸收表示能量在试样内转化为热量的损失。散射是由于样品的不均匀性引起的能量的重定向,包括反射、折射和衍射。扫描激光声显微镜(SLAM)是提供100 MHz下组织超声衰减系数的有用工具。已经开发了许多技术来使用SLAM执行此测量,本报告详细介绍并评估了这些技术。超声速度测量的细节可在相关论文[1],[2]中找到。
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Attenuation Coefficient Measurement Technique at 100 MHz with the Scanning Laser Acoustic Microscope
Absrmcf-There has been a lack of an accurate procedure for the measurement of an attenuation coefficient for biological tissues at 100 MHz with the scanning laser acoustic microscope (SLAM). The solution to this problem has been approached with two general schemes. One involved a calibrated look-up table, and the other utilized the measurement of insertion loss. For the latter a procedure has been developed and verified using known biological solutions. The insertion loss procedure yields an attenuation coefficient uncertainty to within five percent, a dynamic range from 4 to 28 dB/mm. and an insertion loss sensitivity of 0.2 dB. N IMPORTANT tissue characterization property is the ultrasonic attenuation coefficient, which is the decrease in energy of the sound wave when it propagates through a material. The attenuation includes absorption and scattering. Absorption represents the loss of energy into heat within the specimen. Scattering is a redirection of the energy due to the inhomogeneities of the specimen and includes reflection, refraction, and diffraction. The scanning laser acoustic microscope (SLAM) is a useful tool for providing at 100 MHz, the ultrasonic attenuation coefficient of tissue. A number of techniques have been developed to perform this measurement with the SLAM, and this report details and evaluates these techniques. Details of ultrasonic velocity measurements are found in companion papers [l], [2].
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