【儿童期昆虫毒液过敏的特殊问题】。

Allergie und Immunologie Pub Date : 1991-01-01
J Forster, A Eckes, P Hauk, R Urbanek
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引用次数: 0

摘要

膜翅目昆虫过敏的自然病史对儿童的生命威胁小于成人。我们评估了一种常用的风险评分(对指数坐姿的过敏反应,通过皮肤点刺试验和特异性IgE测量的致敏性,特异性IgG -最大8分),以预测即将发生的过敏反应。低分(7分以下)患儿93例发生野外蜇伤,96%未发生严重全身反应。在接受快速低敏治疗的119名高分儿童(大于6分)中,只有32%发生了全身反应。我们得出的结论是,该分数恰当地识别了不需要进行减敏治疗的个体,但它高估了需要进行减敏治疗的儿童数量。因此,我们制定了一项诊断方案,包括挑战刺痛,以确定那些真正需要低敏的儿童。
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[The special problem of insect venom allergy in childhood].

Natural history of hymenoptera sting allergy is less life threatening in children than in adults. We evaluated a commonly used risk score (allergic reaction to the index sitting, sensitization measured by skin prick test and specific IgE, and specific IgG - maximal 8 points) for its predictability of forthcoming allergic reactions. 93 children with low scores (less than 7 points) experienced stings in field, 96% were save from severe systemic reactions. Of 119 children with high scores (greater than 6 points) receiving rush hyposensitization only 32% developed systemic reactions. We conclude that the score appropriately identifies individuals not to be hyposensitized, but that it overestimates the number of children with a need for hyposensitization. We therefore developed a diagnostic scheme including challenge stings to identify those children who really need hyposensitization.

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