印度最近爆发的寨卡病毒及其媒介学和病毒学综述

A. Srivastava, N. Kachhwaha
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引用次数: 2

摘要

寨卡病毒是一种虫媒病毒(节肢动物传播的病毒),属于黄病毒科,于1947年在乌干达寨卡森林的黄热病研究中首次从发热的恒河猴的血液中分离出来,后来在同一森林的非洲伊蚊中发现。但2007年,在雅普岛(密克罗尼西亚联邦)发生了寨卡病毒感染的第一次重大暴发,人们注意到,在那里发生了以皮疹、结膜炎、主观发热、关节痛和关节炎为特征的疾病暴发。大约73%的人口受到感染,其中18%的人患上了有症状的疾病。2015年,巴西报告了约150万例病例。2017年,美国报告了305例病例,2018年,印度(拉贾斯坦邦、古吉拉特邦和中央邦)报告了109例病例。诊断该疾病的最佳方法是RT-PCR,迄今为止还没有疫苗或专门的治疗方法。最可接受的预防方法是减少成蚊的产卵地点。正在继续研究疫苗开发、治疗、药物和预防战略,以根除这种疾病。
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A Review- Recent Outbreak of Zika Viruses in India, its Vectorology and Virology
Zika virus is an arbovirus (arthropod-borne virus) which belongs to the family Flaviviridae that was first isolated in 1947 from blood of a febrile rhesus macaque monkey during a yellow fever study in the Zika forest of Uganda and later identified in  Aedes africanus  mosquito from the same forest. But in 2007, the first major outbreak of Zika virus infection occurred in Yap Island (Federated States of Micronesia), where, it was noticed that an outbreak of illness characterized by rashes, conjunctivitis, subjective fever, arthralgia, and arthritis. Approximately 73% of the population were infected and out of which 18% developed symptomatic disease. In 2015, an estimated 1.5 million cases were reported in Brazil. In 2017, 305 cases were reported from US kingdom and in 2018, 109 cases from India (Rajasthan, Gujrat and Madhya Pradesh). The best method to diagnose the disease is by RT-PCR and till date there is no vaccine or specific treatment available. The most acceptable method for prevention is to reduce egg laying sites of the adult mosquito. Continued researches of vaccine development, treatment, medication and prevention strategies are in progress to eradicate the disease.
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