基于SEIRDV修正模型的黎巴嫩新冠肺炎病例稳健数学模型的建立

A. Fawaz, M. Owayjan, Roger Achkar
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摘要

新冠肺炎大流行引发了一场全球性危机,无论是巨大的全球卫生突发事件,还是全球经济危机形势。这是这一代人面临的最大挑战之一。计算模拟在预测当前的大流行中发挥着巨大的作用。这种模拟能够对未来大流行的预测进行早期预测,并有助于估计针对该病毒采取的控制行动的效率。SEIR(易感-暴露-感染-恢复)模型是计算任何传染性病毒疾病模拟的常用模型,以前广泛用于模拟和模拟SARS、埃博拉、西班牙流感等。本文提出了一个改进的SEIR模型,该模型考虑了死亡率、恢复率和恢复率以及再次感染的机会、疫苗接种率和控制效率等参数;其中控件表示锁定的有效性。控制这一因素是为了将预测扩展到控制死亡、康复和感染。模型中还包括由于控制行动措施造成的流行病发展的时间延迟、人口老龄化因素以及具有时间免疫反应的再易感性等具体信息。然后,考虑疫苗接种率和疫苗效力,对系统加入可控疫苗后的结果进行检验。数值结果表明了该模型的可预测范围。
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Development of a Robust Mathematical Model to Estimate COVID-19 Cases in Lebanon Based on SEIRDV Modified Model
COVID-19 pandemic triggered a global crisis, whether it comes to a huge global health emergency or to the global economic crisis situation. It is one of the greatest challenges this generation is facing. Computational simulations are playing a huge rule in the prediction of the current pandemic. Such simulations enable early predictions for future projections of the pandemic and are useful to estimate the efficiency of control action taken against this virus. The SEIR (Susceptible-Exposed-Infectious-Recovered) model is a commonly used model to compute the simulations of any infectious viral diseases and was widely used before to model and simulate SARS, EBOLA, Spanish Flu, etc. This paper presents a modified SEIR model with additional parameters taken into consideration such as the death, recovered and recovered with the chance of being infected again, vaccination and control efficiency; where the control represents the effectiveness of the lockdown. This factor is being controlled in order to extend the projections into controlled death, recovery, and infection. Specific information including time delay on the development of the pandemic due to control action measures, ageing factor of the population, and re-susceptibility with temporal immune response are also included in the model. After that, the model examines the outcome of the system after adding a controllable vaccine with taking into consideration the vaccination rate and vaccine’s efficacy. The numerical results are demonstrated to show the predictability range of this model.
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