腹腔镜Heller肌切开术和Dor基底置开术后的健康相关生活质量和长期结果

González Rr, Alfonso Mam, Ramos Rj, Escobar Va, Poyato Sb, P. Mm
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引用次数: 0

摘要

腹腔镜Heller肌切开术目前被认为是缓解食管贲门失弛缓症(EA)患者吞咽困难的首选治疗方法,其胃食管反流发生率低,健康相关生活质量(HRQL)明显改善。目的:评价腹腔镜Heller肌切开术和Dor底扩术后健康相关生活质量和临床进展。材料和方法:前瞻性纵向描述性观察研究,通过胃肠生活质量指数问卷(GIQLI)对2010年1月至2017年12月在国家微创外科中心接受EA手术的患者进行调查。调查问卷分别于手术前和手术一年后使用。统计分析:定性变量以百分数表示,均数±标准差或中位数与极差表示,定量变量视情况而定,对于问卷结果的比较,我们采用学生t检验,具有统计学显著性水平α=0.05。结果:101例患者纳入研究,其中3例被排除。年龄从18岁到78岁不等,平均47岁。症状发展的平均时间为62个月,吞咽困难评分平均为3.3,食管下括约肌静息压(mmHg)为38.7±16.8,初始GIQLI为85,3±20.4,术后12个月增加至131.6±10.5。结论:Heller肌切开术和Dor底扩术可及时改善食管贲门失弛缓症患者的健康相关生活质量。
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Health-Related Quality of Life and Long-term Results after Laparoscopic Heller Myotomy and Dor Fundoplication
Introduction: Laparoscopic Heller myotomy is currently considered the choice treatment for relief of dysphagia in Esophageal Achalasia (EA), showing a low incidence of gastroesophageal reflux and evident improvement in Health-Related Quality of Life (HRQL). Objective: Evaluate Health-Related quality of life and clinic evolution after laparoscopic Heller myotomy and Dor fundoplication. Material and method: Prospective longitudinal descriptive observational study, through the application of the Gastrointestinal Quality of Life Index questionnaire (GIQLI) to patients underwent surgery for EA from January 2010 to December 2017 at the National Center for Minimally Invasive Surgery. The questionnaire was applied before surgery and one year later. Statistical analysis: Percentages for qualitative variables, mean ± standard deviation or median and range, as appropriate for quantitative variables, for the comparison of the questionnaire results, we used student’s t-test, with statistical significance level α=0.05. Results: 101 patients were included in the study, three of them were excluded. Age ranged from 18 to 78 years with an average of 47 years. The mean time of evolution of the symptoms was 62 months, with an average of 3.3 on the dysphagia scale and a Resting Pressure of the lower esophageal sphincter (mmHg) 38.7 ± 16.8, an initial GIQLI of 85 was obtained, 3 ± 20.4, which increased twelve months after surgery to 131.6 ± 10.5. Conclusions: Heller myotomy and Dor fundoplication improve Health-Related quality of life in patients with esophageal achalasia with good outcomes in time.
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