临床特征

G. Lip
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引用次数: 0

摘要

背景:伤寒是一种由伤寒沙门菌和副伤寒沙门菌引起的全身性疾病,存在于受污染的水和食物中。它影响到世界上相当多的人口,但南亚地区最常受到影响。目的与目的:本研究的目的是了解伤寒流行在年龄、性别、婚姻状况、职业、季节变化、生活饮用水源处理、临床特征等方面的差异。方法:这是一项横断面观察性研究,于2019年1月至12月在达卡达蒙迪的孟加拉国医学院医院(BMCH)进行。以发热腹痛为主诉的门诊或住院病人均行血培养诊断伤寒。经知情同意且血培养报告阳性的患者(包括伤寒沙门菌和副伤寒沙门菌)被纳入研究。结果:共检测1375例,其中血培养阳性407例(包括伤寒沙门菌和副伤寒沙门菌)。在这些测试中,31.65%为男性,27.35%为女性。18 ~ 45岁男性伤寒发病率最高,75岁以上男性伤寒发病率最低。至于职业的影响,男性公务员在医院的发生率最高,而工匠的发生率最低。婚姻状况的影响以单身男性最高,已婚女性最低。从月份看,7 ~ 9月患病率最高(11.42%)。水质、疫苗接种和季节对人群伤寒负担有很大影响。发烧、腹泻和腹痛是与伤寒有关的主要症状。结论:年龄、性别、婚姻状况、季节变化、饮水处理、职业、就诊情况等社会人口因素影响着达喀市达蒙地BMCH人群伤寒的分布格局。
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Clinical features
Background: Enteric fever otherwise called Typhoid fever is a systemic disease caused by Salmonella typhi and Salmonella paratyphi, having reservoir in contaminated water and food. It affects considerable number of populations of the world but regions of South Asia are most commonly affected. Aims and Objective: The objective of this study to find the prevalence of Typhoid fever with respect to age, gender, marital status, occupation, seasonal variation, treatment of drinking domestic water source, and clinical features. Methodology: This is a crosssectional observational study conducted at Bangladesh Medical College Hospital (BMCH), Dhanmondi, Dhaka from January to December 2019. Those presenting both outpatient departments or admitted to the inpatient units with complains of fever and abdominal pain underwent blood culture for the diagnosis of Typhoid fever. Patients with informed consent and positive blood culture report (including both Salmonella typhi and Salmonella paratyphi) were included in the study. Results: Total 1375 tests were performed, out of which 407 came out to be positive blood culture report (including both Salmonella typhi and Salmonella paratyphi). Out of these tests 31.65% were males and 27.35% were females. Highest occurrence of typhoid fever was observed among males of age group 18 – 45 years and least with patients between age group above 75 years. As for the influence of occupation, male civil servants recorded the highest occurrence in the hospitals while artisans recorded the least. The influence of marital status revealed the highest occurrence in the single males with the married females had the least. In relation to months the prevalence was the highest in the month of July September (11.42%). Water quality, vaccination and season have great impact on the burden of typhoid fever in population. Fever, diarrhea and abdominal pain are the major symptoms associated with typhoid fever. Conclusion: Socio-demographic factors such as age, gender, marital status, and seasonal variation, treatment of drinking water supply, occupation and presenting complaints influenced the distribution pattern of typhoid fever among the population in BMCH, Dhanmondi, Dhaka.
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Investigations Antithrombotic therapy Drug management Management strategies Clinical features
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