阻塞性睡眠呼吸暂停综合征患者的术后镇痛

Alexander Wolfson MD, Robert P. Wong MD, Patricia M. Veloso MD, Christopher L. Wu MD
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引用次数: 4

摘要

尽管最近出版了阻塞性睡眠呼吸暂停(OSA)患者围手术期管理的社会指南,但OSA患者的术后镇痛管理仍存在争议。有许多全身和局部镇痛技术可用于治疗被诊断为OSA的患者的疼痛,但尚不清楚一种药物是否优于另一种。尽管OSA患者的镇痛选择与其他手术患者相似(如全身性阿片类药物、全身性非阿片类药物和局部镇痛技术),但OSA患者的误差幅度较小,术后并发症的可能性较高。术后镇痛的选择应根据患者的具体需要,包括手术类型、共存疾病和恢复部位。虽然常识提示术后应尽量减少阿片类药物和镇静剂的使用,而非阿片类药物和局部镇痛技术的使用应最大化,但很少有随机数据支持这些观点。然而,接受外科手术的OSA患者应接受局部镇痛和非阿片类药物(如非甾体抗炎药)的使用,如果没有禁忌症。需要进一步的研究来检验不同的镇痛方案对OSA患者预后的影响。
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Postoperative analgesia for patients with obstructive sleep apnea syndrome

Despite recent publication of societal guidelines on the perioperative management of obstructive sleep apnea (OSA) patients, the postoperative management of analgesia for patients with OSA is controversial. There are a number of systemic and regional analgesic techniques which may be used for the management of pain in the patient with a diagnosis of OSA but it is unclear if there are advantages of one agent over another. Although the analgesic options for patients with OSA are similar to the options to other surgical patients (e.g., systemic opioids, systemic non-opioids, and regional analgesic techniques), there is a smaller margin for error and the potential for a higher likelihood of complications in the postoperative period for OSA patients. The choice of postoperative analgesia should be tailored to the individual patient’s need including the type of surgical procedure, co-existing diseases, and location of recovery. Although common sense suggests that the postoperative use of opioids and sedative should be minimized while that for non-opioid agents and regional analgesic techniques should be maximized, there is little randomized data to support these notions. Nevertheless, patients with OSA who undergo surgical procedures should receive regional analgesia and non-opioid agents (e.g., NSAIDs) if there are no contraindications for their use. Further studies are needed to examine the different analgesic regimens on OSA patient outcomes.

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