脊索瘤(附11例报告)。

E De Santis, G Gasparini, F Pallotta, P Lisai
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引用次数: 0

摘要

本文报告了11例脊索瘤,其中骶骨脊索瘤3例,腰椎脊索瘤6例,颈椎脊索瘤2例。作者描述了肿瘤的临床和病理表现,并强调脊柱定位的特殊性和诊断的困难,通常是延迟的,特别是在骶骨脊柱定位。放疗和化疗效果不佳,而由于肿瘤发展缓慢且不常发生转移,可采用手术治疗。然而在骶椎的特殊位置允许切除整个肿瘤只要肿瘤位于第二骶椎以下;作者提出了这样一个病例的治疗方法,骶骨和尾骨的次全切除术。在骶骨近端定位和其他脊柱定位中,手术是一种姑息性手术,只能减缓肿瘤的发展;复发是一个规律,即使与放疗有关。然而,由于脊髓根受累,必须经常进行手术治疗。
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[Chordoma (a review of 11 cases)].

Eleven cases of chordoma, localized at sacrum (3 cases), lumbar spine (6 cases), cervical spine (2 cases), are reported. Authors describe clinical and pathological findings of the tumor and underline peculiarity of spinal localization and difficulty of diagnosis, often delayed, particularly in sacral spine localizations. Radiotherapy and chemotherapy give poor results while surgery can be employed in the treatment on account of the slow evolution and of the not very frequent aptitude of the tumor to give metastases. However peculiar localization into the sacral spine allows to remove the whole tumor if only it is localized below the 2nd sacral vertebra; authors present such a case treated by means of subtotal resection of sacrum and coccyx. In proximal sacral localizations and in other spinal localizations, surgery is a palliative procedure and can only slow down the evolution of the tumor; recurrence is a rule, even in association with radiotherapy. However surgical treatment must be often performed because of myeloradicular involvement.

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