关节滑膜内膜和内膜下的超微结构。

M Fadda, G Zirattu, A Marrone
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引用次数: 0

摘要

在扫描和透射显微镜下研究了退行性关节疾病患者手术切除的滑膜。结果表明,滑膜折叠成平均尺寸的绒毛(微绒毛和大绒毛),并伸入关节腔。绒毛的形态是局部可变的,萎缩硬化区与增生区交替,但在地形上有明确的定义。在最后一种情况下,内膜的结构改变以B滑膜细胞的肥大为特征,与其他细胞类型相比,B滑膜细胞是构成细胞和优势细胞。在扩张血管周围的内膜下,可发现垂体后叶炎性浸润。这些改变是活性生物过程的结果,因此滑膜在骨关节炎的发展中起着重要作用。
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[The ultrastructural aspects of the synovial intima and subintima in arthrosis].

Synovial membrane removed surgically from patients during developing degenerative joint disease were studied under a scanning and transmission microscope. The results show that the synovial membrane is folding into villi of average dimensions (microvilli and macrovilli) which project into articular cavity. In regard to the villi, the morphology is locally changeable, with the atrophic-sclerotic areas alternated with hyperplastic areas, but topographically well defined. In the last ones, structural modifications of the intima layer, are characterized by hypertrophy of B synoviocytes, which are constituent and predominant cells in comparison with other cell-types. In the subintima around ectatic vessels, the linfomonocitary inflammatory infiltrations may be found. These alterations are the results of active biological process and because of this synovial membrane is of big importance in developing of osteoarthritis.

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