临床试验与精准医疗区块链平台设计

Zonyin Shae, J. Tsai
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引用次数: 156

摘要

本文提出了一种用于临床试验和精准医疗的区块链平台架构,并对其设计的各个方面进行了讨论,并对其技术需求和挑战提出了一些见解。我们确定了需要在传统区块链平台上构建的4个新的系统架构组件,并讨论了它们在区块链平台上面临的技术挑战:(a)一个新的基于区块链的通用分布式并行计算范式组件,用于设计和研究大数据分析的并行计算方法;(b)区块链应用数据管理组件,用于数据完整性、大数据集成和整合医疗相关数据的差异;(c)可验证的匿名身份管理组件,用于个人和物联网(IoT)设备的身份隐私和安全数据访问,以实现以患者为中心的医疗,以及(d)信任数据共享管理组件,以实现协作研究的信任医疗数据生态系统。
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On the Design of a Blockchain Platform for Clinical Trial and Precision Medicine
This paper proposes a blockchain platform architecture for clinical trial and precision medicine and discusses various design aspects and provides some insights in the technology requirements and challenges. We identify 4 new system architecture components that are required to be built on top of traditional blockchain and discuss their technology challenges in our blockchain platform: (a) a new blockchain based general distributed and parallel computing paradigm component to devise and study parallel computing methodology for big data analytics, (b) blockchain application data management component for data integrity, big data integration, and integrating disparity of medical related data, (c) verifiable anonymous identity management component for identity privacy for both person and Internet of Things (IoT) devices and secure data access to make possible of the patient centric medicine, and (d) trust data sharing management component to enable a trust medical data ecosystem for collaborative research.
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