Zoonoses and biosecurity at zoo, where can work as a wildlife health center for One Health

: The emerging coronavirus pandemic has severe impacts on One Health globally. Diseases, zoonoses, and biosecurity are important emerging issues for species conservation at the world zoos. Zoos emphasize public health to protect visitors and zoo staff, and animal hygiene to manage the good health. There is no border between on a zoo ground and neighboring natural environment. Therefore, zoo biosecurity including preventive medicine protocols to protect the animals from infectious diseases transmitted by wildlife are routinely conducted. Infectious diseases of captive animals should be prevented to spread outside. Investigation of rescued wildlife and necropsies of the carcasses found on zoo grounds must be useful monitoring tools of wildlife diseases and provide a baseline measure of the risk by local wildlife. A sparrow mass mortality caused by emerging salmonellosis in Hokkaido, 2008 ‒ 2009. The initial case found dead on a zoo ground was investigated as a preventive medicine program to protect the captive animals and biosecurity. Zoos can work as wildlife disease information networks and an early warning system by monitoring wildlife diseases and conducting biosecurity countermeasures.