戒酒者的睡眠特征。酒精和年龄导致的深度睡眠减少的比较[j]。

B Kurella, A Heitmann, S Dormann, K Meister
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引用次数: 0

摘要

对12例清醒酗酒者、8例青年正常人和12例健康老年人进行多波睡眠记录。采用自动睡眠分析,包括两种不同的SWS评分方法(标准和自适应)。标准方法基于Rechtschaffen和Kales的振幅相关规则。自适应方法对SWS进行分类的依据是NREM睡眠期间综合δ活动的相对增加。在年轻和年老的正常受试者中,所使用的方法对夜间SWS的持续时间没有影响,而在应用适应性睡眠分析时,与标准方法的结果相比,酒精患者的SWS数量明显更高。根据标准睡眠分析,酗酒者在非快速眼动期间的综合三角洲活动水平最低,同时也是持续时间最短的SWS。与此相反,自适应睡眠分析测量的脑电同步的相对动态和SWS持续时间与正常受试者的值相当。在清醒的酗酒者睡眠期间,delta活动的普遍减少被认为不是SWS减少的反映。
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[Characteristics of sleep in abstinent alcoholics. A comparison of alcohol- and age-induced reduction of deep sleep].

Polygraphic sleep recordings were performed in 12 sober alcoholic patients, 8 young normals and 12 healthy elderly subjects. An automatic sleep analysis including two different methods (standard and adaptive) of SWS scoring was used. The standard method is based on amplitude dependent rules according to Rechtschaffen and Kales. The basis for classification of SWS in the adaptive method is the relative increase of the integrated delta-activity during NREM sleep. Whereas in young and elderly normal subjects the method used has no influence on the duration of SWS during the night, the amount of SWS in alcoholic patients is significantly higher when applying the adaptive sleep analysis compared with the results of the standard method. Alcoholics show the lowest level of integrated delta activity during NREM and also the shortest duration of SWS resulting from the standard sleep analysis. On the contrary the relative dynamic of EEG synchronization and the duration of SWS measured by the adaptive sleep analysis are comparable with the values of normal subjects. The general decrease of the delta activity during sleep in sober alcoholics is assumed to be not a reflection of the reduction of SWS.

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