腹腔镜卵巢钻孔对抗勒管激素、LH/FSH比值及抑制素B的影响

Ezeldin Mohamed, M. E. M. Mohamed, M. A. Taha, I. Abozeid
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引用次数: 1

摘要

目的:比较AMH与卵巢储备(OR)的其他参数,评价腹腔镜卵巢钻孔术(LOD)对卵巢储备(OR)的影响。结果:妊娠组和未妊娠组术前平均AMH水平分别为6.9±1.4 ng/ml和8.2±1.4 ng/ml。术后3个月,妊娠组和未妊娠组的平均AMH水平分别为5.1±1.1 ng/ml和6.3±1.4 ng/ml。妊娠组和未妊娠组术前平均LH/FSH比值分别为2.04±0.5和3.02±0.6。术后3个月,已怀孕组和未怀孕组的平均LH/FSH比值分别为1.15±0.2和1.93±0.6。妊娠组和未妊娠组术前平均抑制素B水平分别为52.5±2.2 pg/ml和52.6±3.9 pg/ml。术后3个月,妊娠组和未妊娠组的平均抑制素B水平分别为48.3±2.1 pg/ml和49.1±3.6 pg/ml。结论:多囊卵巢综合征(PCOS)患者术前LH/FSH比值及AMH水平与妊娠率有显著相关性,而术前抑制素B水平与妊娠率无显著相关性。
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The effect of Laparoscopic Ovarian Drilling on Anti-Müllerian Hormone, LH/FSH ratio & Inhibin B
Aim of The Work: Comparing AMH to other parameters of ovarian reserve (OR) in evaluating the effect of laparoscopic ovarian drilling (LOD) on OR in treatment of PCO.Results: The mean AMH level before the operation was 6.9±1.4 ng/ml & 8.2±1.4 ng/ml for the patients who got pregnant and those who did not get pregnant respectively. While the mean AMH level after 3 months of the operation was 5.1±1.1 ng/ml & 6.3±1.4 ng/ml for the patients who got pregnant and those who did not get pregnant respectively. The mean LH/FSH ratio before the operation was 2.04±0.5 & 3.02±0.6 for the patients who got pregnant and those who did not get pregnant respectively. While the mean LH/FSH ratio after 3 months of the operation was 1.15±0.2 & 1.93±0.6 for the patients who got pregnant and those who did not get pregnant respectively. The mean inhibin B level before the operation was 52.5±2.2 pg/ml & 52.6±3.9 pg/ml for the patients who got pregnant and those who did not get pregnant respectively. While the mean inhibin B level after 3 months of the operation was 48.3±2.1 pg/ml & 49.1±3.6 pg/ml for the patients who got pregnant and those who did not get pregnant respectively.Conclusion: Pregnancy rates were significantly related to the preoperative LH/FSH ratio & AMH levels when comparing the cases that got pregnant with the cases who did not conceive postoperatively in patients of polycystic ovary syndrome (PCOS), whereas preoperative Inhibin B level had no relation to pregnancy rates .
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