急性乙型肝炎患者血清抗hbc聚合IgA抗体。

A Angeretti, B Ferrara, A Biglino, C Merlino, A Negro Ponzi
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引用次数: 0

摘要

血清抗hbc IgA抗体可在急性乙型肝炎患者中得到证实。起初,它们主要是聚合IgA (p-IgA),而单体IgA (m-IgA)在3个月后可检测到。在大多数情况下,6-12个月后不能证明抗hbc IgA。从诊断的角度来看,特异性p-IgA可视为活动性感染的标志,但与IgM相比,它们的证明更加困难。
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Anti-HBc polymeric IgA antibodies in serum from acute hepatitis B patients.

Serum anti-HBc IgA antibodies can be demonstrated in acute hepatitis B patients. At first, they are mainly polymeric (p-IgA), whereas monomeric IgA (m-IgA) become detectable 3 months later. In most cases, anti-HBc IgA cannot be demonstrated after 6-12 months. From a diagnostic point of view, specific p-IgA can be regarded as a marker of active infection but, compared to IgM, their demonstration is more difficult.

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