胃癌患者外周血淋巴细胞对脑啡肽、多巴胺和血清素的敏感性。

Eksperimental'naia onkologiia Pub Date : 1990-01-01

D D Kharkevich, G I Gubina, Z G Kadagidze

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引用次数: 0

摘要

血液淋巴细胞对met-enkephalin和多巴胺刺激作用的敏感性在胃癌晚期(IIIB-IV)或转移到其他器官的情况下下降，而对血清素抑制作用的敏感性较早期(I-IIA)增加。使用特定的阿片受体阻滞剂，多巴胺受体和血清素受体，表明这些作用是通过刺激各自的类型受体介导的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[The sensitivity of the blood lymphocytes in stomach cancer patients to met-enkephalin, dopamine and serotonin].

Sensitivity of blood lymphocytes to the stimulating effect of met-enkephalin and dopamine was shown to decrease at late stages of the gastric cancer (IIIB-IV) or in the case of metastases to other organs, while to the inhibitory effect of serotonin it increased as compared to early stages (I-IIA). Using specific blockers of opioid, dopamine and serotonin receptors it was shown that these effects were mediated through stimulation of respective type receptors.

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Eksperimental'naia onkologiia

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