[反应性淋巴结病的微生物学和形态学发现]。

A Sauerbrei, P Wutzler, W Pfister, U Kaiser, D Schreiber, K D Rüdiger
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引用次数: 0

摘要

用微生物学和组织形态学方法对52例反应性淋巴结病的诊断进行了探讨。血清学结果与临床完整个体的记录不同,不仅包括抗体的流行率增加,而且巨细胞病毒、流感病毒和刚地弓形虫的抗体滴度也增加。对18例涉及上述病原体的活动性感染患者中的11例进行了疱疹病毒、流感病毒和刚地弓形虫抗原特异性抗体滴度动态随访,结果显示阳性。组织学上,受影响的淋巴结表现为类似皮林格淋巴结炎的改变。然而,在细菌学调查过程中,从35例患者的淋巴结组织中分离到各种细菌,从淋巴结切片直接形态学鉴定失败。不成熟的窦组织细胞增多和吞噬活性增加是典型的组织表现。
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[Microbiological and morphological findings in reactive lymphadenopathy].

An attempt was made by means of microbiological and histomorphological methods for diagnostic elucidation of reactive lymphadenopathies in 52 patients. The serological findings differed from those recorded from clinically intact individuals, in that they included not only increased prevalence of antibodies but also increased antibody titres to cytomegalovirus, influenza virus, and toxoplasma gondii. The dynamic of antibody titres against antigens specific of herpesvirus, influenza virus, and toxoplasma gondii were followed up and enabled positive detection in 11 of 18 patients of active infections with the above pathogens involved. Histologically, the lymph nodes affected were characterised by alterations reminiscent to Piringer lymphadenitis. While, in the course of bacteriological investigations, various bacterial species were isolated from lymph node tissue of 35 patients, direct morphological identification from lymph node sections failed to work. Immature sinus histiocytosis and an increase in phagocytosis activity were among the typical tissue findings.

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