牛白血病病毒抗原在flk44 /2培养细胞中表达的免疫细胞化学分析

Eksperimental'naia onkologiia Pub Date : 1990-01-01
A I Nemeĭkaĭte, D I Adomaĭtene
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引用次数: 0

摘要

研究了BLV抗原在产病毒培养物flk44 /2细胞中的表达。用免疫细胞化学方法监测抗病毒多克隆和单克隆抗体与产生病毒的培养细胞的反应性,揭示了细胞群在不同形式和病毒表达水平上的异质性。在体外群体发育过程中,与抗病毒抗体反应的细胞数量的变化被认为是细胞生长周期依赖过程的结果。
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[Immunocytochemical analysis of bovine leukemia virus antigen expression in cells of FLK 44/2 culture].

The expression of BLV antigens has been studied in cells of virus-producing culture FLK 44/2. Monitoring of reactivity of antiviral polyclonal and monoclonal antibodies with cells of the virus-producing culture performed immunocytochemically has revealed the heterogeneity of the cell population both by different forms and by the level of viral expression. A change in the amount of cells reacting with antiviral antibodies during development of the population in vitro is considered as a result of the cell growth cycle-dependent process.

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