细菌转位的调节。

N Kleckner
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引用次数: 66

摘要

细菌转座子受多种调控过程影响转座子事件的数量、质量和时间。这些过程中的许多似乎是专门设计来提供有利于元素进化成功的特性的。从这些调节机制的鉴定和表征中得出的最重要的结论是,转座因子不是最近起源的机械事故,而是高度进化的实体,已经适应了其生态位,其复杂程度可与质粒和细菌病毒所展示的程度相比较。
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Regulation of transposition in bacteria.

Bacterial transposons are subject to a variety of regulatory processes that affect the quantity, quality, and timing of transposition events. Many of these processes seem specifically designed to provide features that favor the evolutionary success of the element. The most important conclusion reached from the identification and characterization of these regulatory mechanisms is that transposable elements are not mechanistic accidents of recent origin, but instead are highly evolved entities that have adapted to their ecological niche with a degree of sophistication comparable to that exhibited by plasmids and bacterial viruses.

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