药物注射剂液体颗粒检测的联合深度学习与聚类算法

M. Zhao, Hui Zhang, Li Liu, Zhicong Liang, Guang Deng
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引用次数: 5

摘要

目前,药物注射产品的检测是药品生产中相当重要的一步,直接关系到药品质量的好坏。针对药物液体颗粒在高分辨率图像检测中像素点较小的困难,考虑结合深度神经网络和聚类算法对小颗粒进行检测和定位,提出了一种单帧图像与多帧图像相结合的液体颗粒识别处理方法。首先,利用Faster-RCNN深度神经网络对单帧图像进行检测,得到8帧序列图像的检测结果。然后采用分层聚类和K-means聚类算法进行聚类,得到相同的目标运动区域。这样可以更准确地识别液体颗粒,大大提高检测的准确性。实验结果表明,该方法对药液中异物的检测识别准确率平均提高10%以上。
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Joint Deep Learning and Clustering Algorithm for Liquid Particle Detection of Pharmaceutical Injection
At present, the detection of pharmaceutical injection products is a quite important step in the pharmaceutical manufacturing, as it has the direct related to the quality of medical product quality. Aiming at the difficulty that liquid particle has a smaller pixel point in the high resolution image of detection of pharmaceutical liquid particle, hence consider combined with deep neural network and clustering algorithm for detection and localization of little particle, and a processing method combining single frame images with multi-frame images was proposed to identifying liquid particle. Firstly, the single-frame image is detected by using Faster-RCNN deep neural network, and it can obtain the detection result of the 8-frame sequence image. Then hierarchical clustering and K-means clustering algorithm are used for clustering to obtain the same target motion area. In this way, liquid particle can be more accurately identified and the accuracy of detection can be greatly improved. The experimental results show that the accuracy of detection and recognition of foreign substances in liquid medicine is improved by more than 10% on average.
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