[肿瘤细胞中多胺修饰的核染色质的增殖动力学和酸溶蛋白]。

Eksperimental'naia onkologiia Pub Date : 1990-01-01

G Z Negreĭ, Iu V Ianish, M P Zavelevich, V A Shliakhovenko

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引用次数: 0

摘要

DFMO对多胺合成的抑制(2.7 × 10(-3) M)导致L和OH-1细胞增殖率下降。通过SDS电泳研究了酸溶性核蛋白的形态。分子量为25 kD的蛋白质组分的含量与细胞培养的增殖率相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[The proliferative kinetics and acid-soluble proteins of the nuclear chromatin in tumor cells with a modified polyamine level].

The inhibition of polyamine synthesis by DFMO (2.7 x 10(-3) M) resulted in a decrease of proliferation rate of L and OH-1 cells. The patterns of acid-soluble nuclear proteins were studied by the SDS electrophoresis. The content of protein fraction with molecular weight 25 kD was shown to correlate with the rate of proliferation of cell cultures.

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Eksperimental'naia onkologiia

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