诱导化疗后下咽及声门上癌经口视腔喉镜手术治疗

伸吾 田中, 雅之 冨藤, 幸仁 荒木, 彰浩 塩谷
{"title":"诱导化疗后下咽及声门上癌经口视腔喉镜手术治疗","authors":"伸吾 田中, 雅之 冨藤, 幸仁 荒木, 彰浩 塩谷","doi":"10.5426/LARYNX.28.61","DOIUrl":null,"url":null,"abstract":"We performed transoral videolaryngoscopic surgery (TOVS) for hypopharyngeal and supraglottic cancer after induction chemotherapy. The data of 24 patients with hypopharyngeal and supraglottic cancer were retrospectively analyzed. The main tumor site was the hypopharynx in 20 cases and the supraglottis in 4 cases. The number of patients with stage II, III, IVA and IVB tumors were 3 , 4 , 15 and 2 , respectively. Although the mean observation period was relatively short (33 months), the 3-year overall survival was 86%, the disease-specific survival was 94% and the laryngeal preservation rate was 94%. The oncological results and laryngeal preservation rate were excellent. The pathological findings showed that caution must be taken against local recurrence because of possible satellite residual cancer. In principle, the resection area should be set according to the original tumor extension. Although the resection area was reduced in some cases, we cannot conclude whether or not the resection area can be safely reduced in all cases. We also examined the need for adjuvant (chemo) radiotherapy. If the resection area was set according to the original tumor extension, negative margin, pT1-2 and pN0-1 , adjuvant radiation therapy may be preserved.","PeriodicalId":126820,"journal":{"name":"THE LARYNX JAPAN","volume":"94 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Transoral Videolaryngoscopic Surgery for Hypopharyngeal and Supraglottic Cancer after Induction Chemotherapy\",\"authors\":\"伸吾 田中, 雅之 冨藤, 幸仁 荒木, 彰浩 塩谷\",\"doi\":\"10.5426/LARYNX.28.61\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We performed transoral videolaryngoscopic surgery (TOVS) for hypopharyngeal and supraglottic cancer after induction chemotherapy. The data of 24 patients with hypopharyngeal and supraglottic cancer were retrospectively analyzed. The main tumor site was the hypopharynx in 20 cases and the supraglottis in 4 cases. The number of patients with stage II, III, IVA and IVB tumors were 3 , 4 , 15 and 2 , respectively. Although the mean observation period was relatively short (33 months), the 3-year overall survival was 86%, the disease-specific survival was 94% and the laryngeal preservation rate was 94%. The oncological results and laryngeal preservation rate were excellent. The pathological findings showed that caution must be taken against local recurrence because of possible satellite residual cancer. In principle, the resection area should be set according to the original tumor extension. Although the resection area was reduced in some cases, we cannot conclude whether or not the resection area can be safely reduced in all cases. We also examined the need for adjuvant (chemo) radiotherapy. If the resection area was set according to the original tumor extension, negative margin, pT1-2 and pN0-1 , adjuvant radiation therapy may be preserved.\",\"PeriodicalId\":126820,\"journal\":{\"name\":\"THE LARYNX JAPAN\",\"volume\":\"94 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"THE LARYNX JAPAN\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5426/LARYNX.28.61\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"THE LARYNX JAPAN","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5426/LARYNX.28.61","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

我们对诱导化疗后的下咽癌和声门上癌行经口视频喉镜手术治疗。回顾性分析24例下咽及声门上癌患者的临床资料。主要肿瘤部位为下咽20例,声门上4例。II期、III期、IVA期和IVB期肿瘤患者分别为3例、4例、15例和2例。虽然平均观察期较短(33个月),但3年总生存率为86%,疾病特异性生存率为94%,喉部保存率为94%。肿瘤结果及喉保存率均良好。病理结果表明,由于可能存在卫星残留癌,必须警惕局部复发。原则上,切除面积应根据原肿瘤的扩展范围设置。虽然部分病例缩小了切除面积,但我们不能断定是否所有病例都能安全缩小切除面积。我们还研究了辅助(化疗)放疗的必要性。如果根据原肿瘤扩展、阴性切缘、pT1-2和pn1 -1确定切除面积,则可以保留辅助放疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Transoral Videolaryngoscopic Surgery for Hypopharyngeal and Supraglottic Cancer after Induction Chemotherapy
We performed transoral videolaryngoscopic surgery (TOVS) for hypopharyngeal and supraglottic cancer after induction chemotherapy. The data of 24 patients with hypopharyngeal and supraglottic cancer were retrospectively analyzed. The main tumor site was the hypopharynx in 20 cases and the supraglottis in 4 cases. The number of patients with stage II, III, IVA and IVB tumors were 3 , 4 , 15 and 2 , respectively. Although the mean observation period was relatively short (33 months), the 3-year overall survival was 86%, the disease-specific survival was 94% and the laryngeal preservation rate was 94%. The oncological results and laryngeal preservation rate were excellent. The pathological findings showed that caution must be taken against local recurrence because of possible satellite residual cancer. In principle, the resection area should be set according to the original tumor extension. Although the resection area was reduced in some cases, we cannot conclude whether or not the resection area can be safely reduced in all cases. We also examined the need for adjuvant (chemo) radiotherapy. If the resection area was set according to the original tumor extension, negative margin, pT1-2 and pN0-1 , adjuvant radiation therapy may be preserved.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Instruction for the Patient to Speak Out for the Monitoring the Voice During Type I Thyroplasty The Role of Bilateral Interactions within the Dorsal Aspect of the Swallowing Central Pattern Generator in Juvenile Rats Involvement from the Limbic System to Spasmodic Dysphonia What does the Otolaryngologist do in Cases of Severe Dysphagia Five Cases of Laryngeal Paralysis Caused by Varicella-zoster Virus Reactivation
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1