辐射诱发多发性口腔癌1例

T. Mikami, A. Funayama, Shohei Kanemaru, Kanae Niimi, S. Maruyama, Tadaharu Kobayashi
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摘要

一名60岁女性因上颌牙槽右侧疼痛来我院就诊。7年前,她因舌左缘鳞状细胞癌(SCC)在另一家医院接受了部分舌骨切除术和术后辅助放疗。首次就诊时的体格检查显示,右上颌骨、左脸颊和前下颌骨的唇龈有肿瘤病变。行活检,病理诊断均为SCCs。患者同时行上颌部分切除、颊部肿瘤切除及下颌骨边缘切除术。由于原发肿瘤不受控制和淋巴结转移,患者在最初治疗3年后死亡。
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A Case of Radiation-induced Multiple Oral Cancer
: A 60-year-old female visited our hospital with pain in the right side of the maxillary alveolus. Seven years before visiting our hospital, she had undergone partial glossectomies and postoperative adjuvant radiotherapy due to squamous cell carcinoma (SCC) of the left margin of the tongue at another hospital. Physical examination at the first presentation revealed tumorous lesions in the right maxilla, left cheek and labial gingiva of the anterior mandible. Biopsies were performed and the pathological diagnoses were SCCs for all biopsies. The patient underwent partial max-illectomy, resection of the buccal tumor, and marginal mandibulectomy simultaneously. The patient died 3 years after the initial treatments because of the uncontrolled primary tumor and lymph node metastases.
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